Interactions | Methylphenidate

Interactions

The following drugs may interact with methylphenidate. You should inform your doctor about any medication you are taking. Caution is advised with these drugs:

  • MAO inhibitors
  • Guanethidine
  • Amantadine
  • Tricyclic antidepressants
  • Neuroleptics
  • Antiepileptic drugs
  • Anticoagulants
  • H2 Blocker
  • Alcohol

Is methylphenidate available over the counter?

Methylphenidate belongs to the group of amphetamines and is therefore not only subject to prescription, but in Germany is even subject to the narcotics law. Nevertheless, there are numerous providers, especially on the Internet, from whom the drug can be purchased in an apparently legal way without a prescription. From a medical and legal point of view, however, such a purchase is strongly discouraged. Methylphenidate should only be taken by people for whom it is indicated for the treatment of a disease. In addition, although one does not always have to fear a penalty for illegitimate purchase of the substance on the Internet, one is violating a law that exists for good reason to protect against potentially harmful substances.

Methylphenidate and alcohol

The consumption of alcohol in any form is strongly discouraged when taking methylphenidate. It can lead to unpredictable side effects. The risk increases with the amount of alcohol consumed and life-threatening situations can occur.

For example, some people who took methylphenidate have experienced an unintentional suicide after drinking large amounts of alcohol. In addition to these direct dangers, alcohol also impairs the desired effects of methylphenidate in the treatment of conditions such as attention deficit syndrome (ADHD). Methylphenidate (Ritalin®), which belongs to the group of psychotropic drugs, shows interactions with various drugs.

In addition, psychotropic drugs and alcohol should not be taken together. If alcohol and methylphenidate are taken at the same time, there is a risk of dopamine overdose in the body. It has been shown that the breakdown of alcohol is more difficult or significantly delayed in some of those affected.

Even the smallest amounts of alcohol should be avoided, as the interaction is not calculable, and alcohol poisoning can be the result. Dopamine is a messenger substance that acts as a neurotransmitter. As such, dopamine transmits excitation from one nerve cell to other cells.

The hormone is responsible for the transmission of feelings and sensations. If the dopamine concentration in the brain is too high, too many impressions and feelings are perceived and the person concerned loses the ability to distinguish between important and unimportant impressions. Too high a dose of dopamine can lead to psychosis or schizophrenia.

Dopamine acts as a sympathetic mimetic (it increases the effect of the sympathetic nervous system). In the body, it also promotes blood circulation to the abdominal organs and leads to increased blood flow to the kidneys. An excess of dopamine can lead to high blood pressure, headaches, palpitations or sweating.