Metatarsal Pain (Metatarsalgia): Or something else? Differential Diagnosis

Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).

  • Brachymetatarsia – relatively rare congenital bone growth disorder; most commonly affects the fourth metatarsal, which stops growing in length earlier than the other bones; most likely autosomal dominant inheritance
  • Hollow foot (pes cavus or pes excavatus).

Musculoskeletal system and connective tissue (M00-M99).

Psyche – nervous system (F00-F99; G00-G99)

  • Morton’s neuralgia (synonyms: Morton’s metatarsalgia, Morton’s syndrome, or Morton’s neuroma) – nerve compression syndrome of the interdigital nerves (nerve branches of the medial plantar nerve and lateral plantar nerve that run between the metatarsals) due to displacement of the nerve-vascular bundle (esp. In the interdigital space D3/4), usually with accompanying bursitis (bursitis); leads to irritation of the nerves of the sole of the foot, which causes seizure-like pain in the area of the metatarsal bones.

Injuries, poisonings and other consequences of external causes (S00-T98).

  • Fracture (fracture) of the metatarsal bone.
  • Instability of the tasometatarsal joints (tarsal-metatarsal joints).
  • Bone/cartilage injuries, unspecified.