The following are the most important diseases or complications that may be contributed to by “mild cognitive impairment”:
Endocrine, nutritional, and metabolic diseases (E00-E90).
- Malnutrition
Cardiovascular system (I00-I99)
- Apoplexy (stroke) – analysis of 18 cohort studies shows that the risk of apoplexy increased in patients with pre-established cognitive impairment.
Psyche – Nervous System (F00-F99; G00-G99).
- Dementia
- Depression
- Insomnia (sleep disorders)
Further
- Patients >75 years of age with newly diagnosed cognitive impairment have a 42% higher risk of death during the subsequent observation period (mean 8.0 years).
- Reduction in gait speed
Prognostic factors
- Low systolic blood pressure was shown to be an independent parameter for faster progression of cognitive decline in elderly patients with dementia and mild cognitive impairment for patients treated with antihypertensives. CONCLUSION: Ambulatory blood pressure monitoring (ABDM) may be useful to avoid hypertension overtreatment in this population.
- Neither antihypertensive medication nor lipid lowering affected cognitive performance in elderly without cardiovascular disease as a primary preventive strategy (observation period: 5.6 years)
