The following procedures are usually used in combination in the treatment of neuroblastoma:
- In stages 1 and 2, surgical tumor removal alone is the goalOperation: tumor resection (the goal is complete removal of the tumor).
- Chemotherapy (in higher stages) before surgery.
- Radiotherapy (in stage 4 in selected tumor localizations).
The following treatment concepts are available:
- Low risk (criteria: Tumor size and no metastasis/formation of daughter tumors and no molecular genetic alterations in the tumor and age of the patient) – Observation of the course after the initial surgery.
- Intermediate risk (criteria: Tumor size and no metastasis/formation of daughter tumors and no molecular genetic changes in the tumor and age of the patient) – Surgery with chemotherapy, radiotherapy if necessary.
- HighRisk (metastasis or presence of molecular genetic unfavorable markers) – surgery with chemotherapy/high-dose chemotherapy, radiotherapy if necessary.
