Nimodipine

Products

Nimodipine is commercially available as an infusion solution and tablets (Nimotop). It has been approved in many countries since 1987.

Structure and properties

Nimodipine (C21H26N2O7, Mr = 418.4 g/mol) is a racemate. It exists as a pale yellow to yellow crystalline powder that is practically insoluble in water.

Effects

Nimodipine (ATC C08CA06) has cerebral antivasoconstrictor and antiischemic properties.

Indications

For prevention and treatment of ischemic neurologic deficits due to cerebral vasospasm following subarachnoid hemorrhage from aneurysms.