Most patients do not have symptoms.
However, the following symptoms and complaints may indicate Paget’s disease:
- Bone pain in the area of the affected bone
- Deformities/thickening/fractures (fractures) of the affected bones.
- Muscle cramps due to incorrect loading
- Overheating of the affected region due to the formation of new vessels
- Gait disturbances
- Osteoarthritis
- Back pain
- Spinal stenosis (narrowing of the spinal canal), possibly with compression of the spinal cord (→ dysfunction and pain or even irritation of the sciatic nerves; typical of spinal stenosis is the symptom of claudication spinalis/pain-related or spinal limping)
- Headache
- Enlargement of the skull (increase in the circumference of the head) with a raised forehead (cerebral skull is unusually large compared to the facial skull)
- Neurological complications due to constriction of the structures of the central nervous system.
- Hearing loss
- Platybasia (flattening of the base of the skull)
- Changes in the appearance of the face
- Tooth loss / damage
- Respiratory obstructions
The disease mainly affects:
- Pelvis
- Femur (thigh bone)
- Skull
- Tibia (shin bone)
- Vertebral body of the lumbar spine
