Products
Pilocarpine has been commercially available in many countries since 2004 in the form of film-coated tablets (Salagen). See also under pilocaprine eye drops.
Structure and properties
Pilocarpine (C11H16N2O2, 208.26 g/mol) is present in the drops as pilocarpine hydrochloride, a white powder or colorless crystals that are very soluble in water. Pilocarpine is an alkaloid from -species (jaborandi leaves).
Effects
Pilocarpine (ATC N07AX01) has parasympathomimetic properties and promotes secretion from the oral salivary glands.
Indications
For the treatment of severe dry mouth, for example after radiotherapy for tumors or in Sjögren’s syndrome.
Dosage
According to the SmPC. Tablets are usually taken up to three times daily during or immediately after meals.
