Sulfites

Products

Sulfites are added to pharmaceuticals, foods and personal care products as excipients and additives. They can also be naturally present in foods. Even the Romans used sulfur dioxide as a preservative for wine.

Structure and properties

Sulfites are the salts of sulfurous acid, which is extremely unstable and undetectable in water (H2SO3). Example sodium sulfite (Na2+SO32-): The hydrogen sulfites, which are also called bisulfites, contain the anion HSO3– −. Metabisulfites have two sulfur atoms bonded together.

Representative

Sulfites and sulfur dioxide permitted as additives:

  • Sulfur dioxide (SO2, E 220)
  • Sodium sulfite (Na2SO3, E 221)
  • Sodium hydrogen sulfite (NaHSO3, E 222)
  • Sodium metabisulfite (Na2S2O5, E 223)
  • Potassium metabisulfite (K2S2O5, E 224)
  • Calcium sulfite (CaSO3, E 226)
  • Calcium hydrogen sulfite (Ca(HSO3)2, E 227)
  • Potassium hydrogen sulfite (KHSO3, E 228)

Effects

Sulfites have antioxidant, preservative and antimicrobial properties.

Fields of application

As preservatives and antioxidants for pharmaceuticals, foods, semi-luxury foods and personal care products. Foods and stimulants containing sulfites include wine, beer, dried fruits, sausages, fish and canned tomatoes (selection).

Contraindications

  • Hypersensitivity

For complete precautions, see the drug label.

Adverse effects

Possible adverse effects include allergic reactions and an intolerance reaction. These include anaphylactoid reactions, skin rashes, edema (swelling), low blood pressure, nausea, vomiting abdominal pain, diarrhea, breathing difficulties, cough, and bronchoconstriction. The adverse effects are potentially life-threatening.