Thyroiditis (Thyroid Gland Inflammation): Test and Diagnosis

Laboratory parameters of the 1st order – obligatory laboratory tests.

  • Small blood count
  • ESR (erythrocyte sedimentation rate) [acute thyroiditis: ESR ↑; subacute thyroiditis: ESR ↑↑]
  • CRP (C-reactive protein) [acute thyroiditis: CRP ↑; subacute thyroiditis: CRP (↑)]
  • Thyroid parameters – TSH (thyroid-stimulating hormone), fT3 (triiodothyronine), fT4 (thyroxine).

Laboratory parameters 2nd order – depending on the results of the history, physical examination and the obligatory laboratory parameters – for differential diagnostic clarification.

  • TRH-TSH test for thyroid function diagnosis.
  • Thyroperoxidase antibodies (= TPO-Ak; thyroid peroxidase antibodies = PAK) or antibodies against microsomal thyroid antigen (microsomal antibodies, microsomal auto-AK = MAK) [Hashimoto’s thyroiditis): TPO antibodies ↑↑↑]
  • Thyroglobulin antibodies (TAK; thyroglobulin autoantibodies (TGAK); thyroglobulin-Ak; Tg-Ak) [Graves’ disease: thyroglobulin autoantibodies (TGAK) detectable in approximately 90% of cases; TPO-Ak in cal 70% of cases]
  • Thyroglobulin (synonym: hTG, TG) – suspected thyroid carcinoma or destructive thyroiditis (thyroiditis de Quervin).
  • Fine needle biopsy – for histological examination.
  • If necessary, pathogen detection after abscess opening.