Antipyretics

Products Antipyretics are available in numerous dosage forms. These include, for example, tablets, effervescent tablets, suppositories, juices, and chewable tablets. The name is derived from the technical term pyrexia (fever). The first synthetic agents, such as acetanilide, salicylic acid, and acetylsalicylic acid, were developed in the 19th century. Structure and properties Antipyretics do not have … Antipyretics

Hydrocodone

Products Hydrocodone was commercially available in tablet form in many countries between 1971 and 2018 (Hydrocodone Streuli, off label). In the United States, it is available in combination with acetaminophen (Vicodin, generic). Structure and properties Hydrocodone (C18H21NO3, Mr = 299.4 g/mol) is present in drugs as hydrocodontartrate (- 2.5 H2O), a white crystalline powder that … Hydrocodone

Metabolism (Biotransformation)

Introduction Biotransformation is an endogenous pharmacokinetic process that leads to a change in the chemical structure of active pharmaceutical ingredients. The organism’s general goal in doing so is to make the foreign substances more hydrophilic and to direct them to excretion via the urine or stool. Otherwise, they could be deposited in the body and … Metabolism (Biotransformation)

Cystitis: Inflammation of the Bladder

Symptoms Acute, uncomplicated bladder infections are among the most common infectious diseases in women. A bladder infection is considered uncomplicated or simple when the urinary tract is functionally and structurally normal and there are no diseases that promote infection, for example, diabetes mellitus or immunosuppression. Symptoms include: Painful, frequent and difficult urination. Strong urge to … Cystitis: Inflammation of the Bladder

Altitude Sickness

Symptoms Symptoms of altitude sickness are nonspecific and usually appear 6-10 hours after ascent. However, they can also occur after as little as one hour: Headache Dizziness Sleep disorders Loss of appetite Nausea and vomiting Fatigue and tiredness Rapid heartbeat Accelerated breathing, shortness of breath Severe symptoms: Cough Shortness of breath even at rest Tightness … Altitude Sickness

Medication Overuse Headache

Symptoms Medication-overuse headache, depending on the preexisting symptoms, manifests, for example, like a tension headache as bilateral, pressing pain, or like a migraine, unilateral, pulsating, and accompanied by nausea, vomiting, and sensitivity to light and noise. The pain occurs chronically for at least 15 days of the month, every other day or daily. When the … Medication Overuse Headache

Oral Mucositis

Symptoms Oral mucositis manifests as redness, swelling, pain, a burning sensation, aphthae, a white to yellowish coating, sores, ulceration, bleeding, and bad breath, among other symptoms. The tongue and gums may also be affected. The discomfort may increase in association with eating. Sores can be so painful that food intake is limited, which can lead … Oral Mucositis

Oral Thrush

Symptoms Oral thrush is an infection of the mouth and throat with Candida fungi. Different manifestations are distinguished. The actual oral thrush is usually called acute pseudomembranous candidiasis. The leading symptom is the white to yellowish, small-spotted, partially intermingled coating of the mucous membranes in the mouth and throat area. It consists of epithelial cells, … Oral Thrush

COVID-19 Vaccines

Products Covid-19 vaccines are in the development and approval phase and are already available in some countries. In many countries, BNT162b2 was the first agent approved on December 19, 2020. mRNA-1273 was approved in the EU on January 6, 2021, and in many countries on January 12, 2021. The first approval will be in Russia … COVID-19 Vaccines

Isoniazid

Products Isoniazid is commercially available in tablet form (eg, Isoniazid Labatec, combination products). Structure and properties Isoniazid (C6H7N3O, Mr = 137.1 g/mol) exists as a white crystalline powder or colorless crystals and is readily soluble in water. It is also known as isonicotinylhydrazine (INH). Effects Isoniazid (ATC J04AC01) has bacteriostatic to bactericidal properties against . … Isoniazid

Paracetamol: Drug Effects, Side Effects, Dosage and Uses

Products Paracetamol is commercially available in the form of tablets, film-coated tablets, melting tablets, effervescent tablets, as granules, drops, syrups, suppositories, soft capsules, and infusion solution, among others (e.g., Acetalgin, Dafalgan, Panadol, and Tylenol). Paracetamol was not approved until the 1950s (Panadol, Tylenol), although it was developed in the 19th century. It has been registered … Paracetamol: Drug Effects, Side Effects, Dosage and Uses

Knee Osteoarthritis

Symptoms Knee osteoarthritis manifests itself as knee pain, which occurs primarily during physical activity and when the joint is under stress. They are often triggered at the beginning of movement (start-up pain), when climbing stairs, when standing up or when walking longer distances. Other complaints include limitation of mobility and quality of life, instability, an … Knee Osteoarthritis