Products Ziconotide is commercially available as an infusion solution (Prialt). It has been approved in many countries since 2006. Structure and properties Ziconotide (C102H172N36O32S7, Mr = 2639 g/mol) is a peptide of 25 amino acids with three disulfide bridges. It is a synthetic analog of the ω-conopeptide MVIIA, which occurs in the venom of the … Ziconotide
Products The combination drug containing the active ingredients tramadol and paracetamol is commercially available in the form of film-coated tablets (Zaldiar). It has been approved in many countries since 2002. In 2014, generic versions went on sale. The effervescent tablets are out of trade. Structure and properties Tramadol (C16H25NO2, Mr = 263.38 g/mol) is a … Tramadol and Paracetamol
Products COX-2 inhibitors (coxibe) are commercially available in the form of film-coated tablets and capsules. The first representatives from this group to be approved in many countries were celecoxib (Celebrex, USA: 1998) and rofecoxib (Vioxx, off label) in 1999. At that time, they rapidly developed into blockbuster drugs. However, due to adverse effects, several drugs … COX-2 Inhibitor
Products Metamizole is commercially available as drops, tablets, suppositories, and injectables (Minalgin, Novalgin, Novaminsulfon Sintetica, generics). It has been used medicinally since the 1920s. Structure and properties Metamizole (C13H17N3O4S, Mr = 311.4 g/mol) is present in drugs as metamizole sodium. This is the sodium salt and monohydrate of the active ingredient. Metamizole sodium is a … Metamizole: Drug Effects, Side Effects, Dosage and Uses
Products Paracetamol is commercially available in the form of tablets, film-coated tablets, melting tablets, effervescent tablets, as granules, drops, syrups, suppositories, soft capsules, and infusion solution, among others (e.g., Acetalgin, Dafalgan, Panadol, and Tylenol). Paracetamol was not approved until the 1950s (Panadol, Tylenol), although it was developed in the 19th century. It has been registered … Paracetamol: Drug Effects, Side Effects, Dosage and Uses
Products Nefopam used to be available in many countries in tablet form (Acupan). It is now no longer commercially available. Structure and properties Nefopam (C17H19NO, Mr = 253.3 g/mol) exists as nefopam hydrochloride, a white crystalline powder that is soluble in water. It is a benzoxazocine derivative. Nefopam is not structurally related to other analgesics. … Nefopam
Products Nonsteroidal anti-inflammatory drugs (NSAIDs) are available in numerous dosage forms. These include film-coated tablets, tablets, sustained-release tablets, oral suspensions, oral granules, suppositories, NSAID eye drops, lozenges, emulsifying gels, and creams (selection). The first active ingredient from this group was salicylic acid, which was used medicinally in the 19th century in the form of the … NSAID
Products Tapentadol is approved in film-coated tablet, sustained-release tablet, and solution forms (Palexia /-retard). It was released in many countries in late February 2011 and went on sale in the fall. Tapentadol, like tramadol (Tramal, generics), was developed at Grünenthal. The sustained-release tablets were approved in 2013 and the solution went on sale in many … Tapentadol
Products Flupirtine is not approved as a drug in many countries. In some European countries, it was commercially available in the form of capsules and suppositories (e.g., Katadolon, Trancopal Dolo), among others. In Germany, flupirtine had been registered since 1989. In 2018, it was withdrawn from the market due to liver toxicity. Structure and properties … Flupirtine
Products Paracetamol is available in suppository form from several suppliers (e.g., Panadol, Acetalgin, Ben-u-ron, Dafalgan, Tylenol). Available dosages include 80, 125, 250, 300, 350, 500, 600, and 1000 mg. Paracetamol suppositories are used primarily in pediatrics, but they can also be given to adults. Structure and properties Paracetamol (C8H9NO2, Mr = 151.2 g/mol) exists as … Paracetamol Suppositories
Products No drugs containing acetanilide are approved in many countries. Antifebrin is no longer on the market. Acetanilide was among the first synthetic analgesics. It was synthesized in the 19th century. Its pharmacological properties were accidentally discovered in the late 1880s. Structure and properties Acetanilide (C8H9NO, Mr = 135.3 g/mol) exists as a white, odorless, … Acetanilide
Products Pain plasters are available as self-adhesive pads in various sizes and compositions at pharmacies and drugstores. Some are approved as medicines, while others are approved as medical devices. In many countries, well-known brands include Flector, Flector Plus, Olfen, ABC, Perskindol, and Isola, for example. This article refers primarily to products approved for self-medication and … Pain Patch
