Carbapenems: Effects, Uses & Risks

Carbapenems are antibiotics that belong to the group of beta-lactams. Originally, carbapenems were called thienamycins. Due to their broad antimicrobial spectrum of activity, they are used as drugs. Some examples are ertapenem, imipenem, doripenem, meropenem and tebipenem. Carbapenems have the status of reserve antibiotics. Within Europe, more and more resistance to carbapenems is being recorded. … Carbapenems: Effects, Uses & Risks

Polymyxins: Effects, Uses & Risks

Polymyxins are antibiotics that mainly fight gram-negative bacteria. However, the active substances act only on bacteria located outside the body cells. The basis of their effectiveness is their reaction with the phospholipids of bacterial cell membranes. What are polymyxins? Polymyxins are antibiotics that fight mainly Gram-negative bacteria. Polymyxins represent intricately branched polypeptides, which usually consist … Polymyxins: Effects, Uses & Risks

Colistin: Effects, Uses & Risks

Colistin is a drug from the group of antibiotics. The polypeptide antibiotic disrupts the permeability of the cell membrane of bacteria, thus killing them. What is colistin? Colistin is a drug from the group of antibiotics. The active ingredient can be used locally as an ointment additive or as an aerosol in inhalation therapy. Colistin … Colistin: Effects, Uses & Risks