Dabigatran

Products Dabigatran is commercially available in capsule form (Pradaxa). It has been approved in many countries since 2012. It was first approved in 2008. Structure and properties Dabigatran (C25H25N7O3, Mr = 471.5 g/mol) is present in drugs as mesilate and in the form of the prodrug dabigatran etexilate, which is metabolized in the organism by … Dabigatran

Amiodarone (Nexterone) for Arrhythmia

Products Amiodarone is commercially available in tablet form and as a solution for injection (Cordarone, generics). It has been approved in many countries since 1968. Structure and properties Amiodarone (C25H29I2NO3, Mr = 645.3 g/mol) is an iodinated benzofuran derivative derived from khellin. It is present in drugs as amiodarone hydrochloride, a white, fine, crystalline powder … Amiodarone (Nexterone) for Arrhythmia

Ranolazine

Products Ranolazine is commercially available in the form of sustained-release tablets (Ranexa). It was approved in the United States as early as 2006, in the EU in July 2008, and in many countries in April 2010. Structure and properties Ranolazine or ()–(2, 6-dimethylphenyl)-4(2-hydroxy-3-(2-methoxyphenoxy)-propyl)-1-piperazine acetamide (C24H33N3O4, Mr = 427.54 g/mol) is a piperazine derivative and a … Ranolazine

Dry Eyes: Causes and Remedies

Background The tear film is the outermost connection between the surface of the eye and the environment and is involved in the visual process. It moisturizes, protects and nourishes the eye. It is an aqueous gel containing water, mucins, salts, antibacterial proteins and antibodies, vitamin A, and lipids, among other substances, and is distributed over … Dry Eyes: Causes and Remedies

Generic

New drugs are protected Newly introduced drugs are usually protected by patent. Another company is not allowed to copy these drugs and distribute them themselves without the manufacturer’s consent. However, this protection expires after a few years. For example, the antidepressant escitalopram (Cipralex) was approved in many countries in 2001 and the patent protection was … Generic

Fosamprenavir: Effects, Uses & Risks

The active medical ingredient fosamprenavir is a so-called antiviral from the family of HIV protest inhibitors. It is used to treat HIV infections and is intended to prevent the development of AIDS (short for Acquired Immune Deficiency Syndrome). Fosamprenavir is marketed under the trade name Telzir and is manufactured by GlaxoSmithKline plc, based in London, … Fosamprenavir: Effects, Uses & Risks

Amiodarone: Effects, Uses & Risks

Amiodarone is used to treat various cardiac arrhythmias. It is administered in tablet form and is known to work well when other antiarrhythmic drugs are unsuccessful in patients. What is amiodarone? Amiodarone is used to treat various cardiac arrhythmias. Amiodarone is a class III antiarrhythmic agent and is used to treat ventricular fibrillation or heart … Amiodarone: Effects, Uses & Risks

Agalsidase

Products Agalsidase is commercially available as an infusion preparation and has been approved in many countries since 2001 and 2003, respectively: Replagal: agalsidase alfa Fabrazyme: agalsidase beta Structure and properties Agalsidase is a recombinant human α-galactosidase A produced by biotechnological methods. The amino acid sequence is identical to the natural lysosomal enzyme. It is a … Agalsidase

Amiodarone

Synonyms in a broader sense Active substance: amiodarone hydrochloride Antiarrhythmics, Action names: Cordarex® Amiogamma® Aminohexal® Cordarex® Amiogamma® Aminohexal® Cordarex® Amiogamma® Aminohexal® The active ingredient amiodarone is used in the treatment of cardiac arrhythmias and the drug is classified as a class III antiarrhythmic drug. Amiodarone can be used to help in cases of disturbed transmission … Amiodarone

Mode of action (for very interested readers) | Amiodarone

Mode of action (for very interested readers) In order for large quantities of blood to circulate continuously in the body’s circulation, the heart needs to be pumped regularly. Heart muscle cells are excited at regular intervals for this purpose. The heart has its own system of impulse conduction, the excitation of the heart muscle cells … Mode of action (for very interested readers) | Amiodarone

Cobicistat: Effects, Uses & Risks

Cobicistat is a medical agent that is used worldwide to treat HIV infection. It is administered exclusively in a so-called HIV combination therapy, i.e. Cobicistat is only used together with other HIV drugs. This enables a holistic fight against the virus, since cobicistat itself has no independent effectiveness against HI viruses. What is cobicistat? Cobicistat … Cobicistat: Effects, Uses & Risks