Symptoms Malaria (Italian, “bad air”) manifests itself in the following symptoms, which usually appear a few weeks after transmission. The incubation period ranges from a few days to several years: High fever, sometimes with rhythmic attacks of fever, every second or third day. However, the fever may also occur irregularly. Chills, profuse sweating. Headache, muscle … Malaria Causes and Treatment
Effects Antiparasitic against plasmodia. Indications Malaria Malaria prophylaxis Also for the treatment of rheumatic diseases, lupus erythematosus. Off-label: some antimalarials such as quinine and chloroquine are used off-label to treat calf cramps. Active ingredients Aminoquinolines: Amodiaquine Chloroquine (Nivaquine, out of commerce). Hydroxychloroquine (Plaquenil) Mepacrine Pamaquin Piperaquine Primaquine Tafenoquin (crinoline) Biguanides: Proguanil (Malarone + Atovaquone). Cycloguanilembonate … Antimalarials
Products Artemether is commercially available as tablets and dispersible tablets as a fixed combination with lumefantrine (Riamet, some countries: Coartem). It has been approved in many countries since 1999. Structure and properties Artemether (C16H26O5, Mr = 298.4 g/mol) is a methyl ether dervate of the sesquiterpene artemisinin from the annual mugwort (, Qing Hao), a … Artemether
Products No drugs containing artesunate are currently approved in many countries. Structure and properties Artesunate (C19H28O8, Mr = 384.4 g/mol) is a succinyl derivative and a prodrug of dihydroartemisinin. It is derived from artemisinin from annual mugwort (, qing hao), a medicinal plant used in traditional Chinese medicine. Effects Artesunate (ATC P01BE03) has antiparasitic properties … Artesunate
