Prolongation of the QT Interval

Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval

Tafenoquine

Products Tafenoquine was approved in the United States in 2018 in tablet form (Krintafel, Arakoda). Structure and properties Tafenoquine (C24H28F3N3O3, Mr = 463.5 g/mol) is an 8-aminoquinoline derivative present in the drug as tafenoquine succinate. It is a derivative of primaquine. The drug was first synthesized in 1978 at the Walter Reed Army Institute of … Tafenoquine

Hydroxychloroquine

Products Hydroxychloroquine is commercially available in the form of film-coated tablets (Plaquenil, auto-generic: Hydroxychloroquine Zentiva). It has been approved in many countries since 1998. Unlike the closely related chloroquine, it is currently on sale. Generic drugs are registered. Structure and properties Hydroxychloroquine (C18H26ClN3O, Mr = 335.9 g/mol) is an aminoquinoline derivative. It is present in … Hydroxychloroquine

Emergency Medication for Self-Treatment

Definition Emergency medications for self-treatment are drugs that are administered in a medical emergency by patients themselves, their relatives, or other instructed persons. They allow rapid and adequate drug therapy of severe to life-threatening conditions without the need for a health care professional to be present. As a rule, the patient should seek medical treatment … Emergency Medication for Self-Treatment

Antiparasitics

Active ingredients See under: Antihelminthics against worm infections. Antiprotozoal agents, e.g., antimalarials and nitroimidazoles (antibiotics) for protozoal infections Insecticides, e.g. antiscabiosa against insects. Flea medication against fleas Repellents against insects Antifungals are also partly counted as antiparasitics – fungal infections.

Antiprotozoal Agent

Indications Infections with protozoa Agents 1. agents for amebiasis, trichomoniasis, and giardiasis: nitroimidazoles: Metronidazole (Flagyl, generic). Tinidazole (Fasigyn, off label). Ornidazole (Tiberal) Other: Atovaquone (Wellvone) Other, not commercially available in this indication: Clioquinol Chlorquinaldol Emetine 2. antimalarials: See under antimalarials 3. agents against leishmaniasis and trypanosomiasis: Pentamidine isethionate (pentacarinate). Eflornithine (Vaniqa, not commercially available for … Antiprotozoal Agent

Quinine

Products Quinine is approved in many countries in the form of dragées for malaria therapy (quinine sulfate 250 Hänseler). In Germany, film-coated tablets of 200 mg quinine sulfate are commercially available for the treatment of calf cramps (Limptar N). Structure and properties Quinine (C20H24N2O2, Mr = 324.4 g/mol) usually exists as quinine sulfate, a white … Quinine

Quinolone

Products The first active ingredient in the quinolone group to be introduced was nalidixic acid in 1967 (NegGram). It is no longer commercially available in many countries. Other drugs are available today (see below). Various dosage forms are available, for example, film-coated tablets, oral suspensions, eye drops, ear drops, and infusion solutions. Due to adverse … Quinolone

Droperidol

Products Droperidol is commercially available as a solution for injection (Droperidol Sintetica). It has been approved in many countries since 2006. Structure and properties Droperidol (C22H22FN3O2, Mr = 379.4 g/mol) structurally belongs to the butyrphenones and exists as a white powder that is practically insoluble in water. It is a benzimidazolinone derivative. Effects Droperidol (ATC … Droperidol

Psoriasis Causes and Treatment

Symptoms Psoriasis is a chronic inflammatory, benign, and noninfectious skin disease. It manifests as symmetrical (bilateral), sharply demarcated, bright red, dry, raised plaques covered by silvery scales. Typically affected areas are the elbows, knees, and scalp. Itching, a burning sensation and pain are other symptoms, and scratching further aggravates the condition. Psoriasis can also affect … Psoriasis Causes and Treatment

Nocturnal Calf Cramps

Symptoms Nighttime calf cramps are painful and involuntary muscle contractions of the legs that often occur in the calves and feet. They last only a few minutes but can continue to cause discomfort for hours. They are particularly common in older people over 60 years of age. They are benign complaints. The most important complication … Nocturnal Calf Cramps

Ebola Causes and Treatment

Symptoms After an incubation period of up to a maximum of three weeks (21 days), the disease begins with nonspecific flu-like symptoms such as fever, chills, feeling sick, digestive disorders and muscle pain. The typical and sometimes uncontrolled bleeding in the skin, mucous membrane and inside the body occurs due to a blood clotting disorder … Ebola Causes and Treatment