P2Y12 Antagonists

Effects P2Y12 antagonists are antiplatelet agents and prevent the formation of blood clots. The effects are due to binding to the adenosine diphosphate receptor P2Y12 on platelets. This receptor plays a central role in glycoprotein (GP)-IIb/IIa activation and platelet aggregation. The continuous binding of adenosine diphosphate (ADP) to P2Y12 is an important prerequisite for thrombus … P2Y12 Antagonists

Aggrenox®

Definition Aggrenox® contains the antiplatelet aggregation inhibitors These active ingredients reduce blood clotting or the clumping of blood platelets, which can reduce the risk of a stroke. – dipyridamole and Acetylsalicylic acid. Manufacturer Boeringer Ingelheim Application areas Aggrenox® is used to prevent further strokes in patients who have already suffered a stroke. Mode of operation … Aggrenox®