Products Black tea is available in grocery stores and specialty stores in bags or open. Different varieties, names and countries of origin exist (e.g. Darjeeling, Ceylon, Pekoe, Assam, English Breakfast Tea, Five o’Clock Tea, Afternoon Tea). Black tea is mainly drunk in the West, while green tea and the semi-fermented oolong tea are more popular … Black Tea
Products Osimertinib was approved in the United States in 2015 and in the EU and Switzerland in 2016 in film-coated tablet form (Tagrisso). Structure and properties Osimertinib exists in the drug product as osimertinib mesilate (C28H33N7O2 – CH4O3S, Mr = 596 g/mol). It is a methylindole, aniline and pyrimidine derivative. Effects Osimertinib (ATC L01XE35) has … Osimertinib
Products Oxaliplatin is commercially available as an infusion concentrate (Eloxatin, generic). It was approved in many countries in 2000 as a third platinum compound for cancer therapy. Structure and properties Oxaliplatin (C8H14N2O4Pt, Mr = 397.3 g/mol) is a platinum compound. It exists as a white crystalline powder and is sparingly soluble in water. Effects Oxaliplatin … Oxaliplatin
Products Tucatinib was approved in the United States and many countries in 2020 in film-coated tablet form (Tukysa). Structure and properties Tucatinib (C26H24N8O2, Mr = 480.5 g/mol) Effects Tucatinib has antitumor and antiproliferative properties. The effects are due to inhibition of HER2 tyrosine kinase. The half-life is approximately 8.5 hours. Indications In combination with trastuzumab … Tucatinib
Products Saffron is commercially available as an expensive spice in the form of threads or powder. Saffron extract is found in dietary supplements. Stem plant Saffron L. from the iris family (Iridaceae) is a perennial plant that is grown extensively in Iran and the Mediterranean region, for example. In many countries, it has been cultivated … Saffron
Products Alpelisib was approved in the United States in 2019 and in many countries in 2020 in film-coated tablet form (Piqray). Structure and properties Alpelisib (C19H22F3N5O2S, Mr = 441.5 g/mol) exists as a white powder. Effects Alpelisib (ATC L01XX65) has antiproliferative and antitumor properties. The effects are due to inhibition of the α-subunit of phosphatidylinositol … Alpelisib
Products Aromatase inhibitors are commercially available in the form of film-coated tablets and coated tablets. The first third-generation agent to be approved in many countries was anastrozole in 1996 (Arimidex, USA 1995). Other drugs are available today. The active ingredients available today all belong to the third generation. Earlier agents such as aminoglutethimide and formestane … Aromatase Inhibitors
Products Afatinib was approved in the US and EU in 2013 and in many countries in 2014 in film-coated tablet form (Giotrif). Structure and properties Afatinib (C24H25ClFN5O3, Mr = 485.9 g/mol) is a 4-aniline quinazoline derivative that is present in drugs as afatinib dimaleate, a white to brownish-yellow powder that is soluble in water. It … Afatinib
Products Licorice is available as cut open or in the form of licorice stems in pharmacies and drugstores. Licorice extract is found in bronchial pastilles, in teas, and various cough medicines, among other products. The extract is also a component of licorice and corresponding confectionery. Stem plant Stem plants include various -species of the legume … Sweet Wood
Products Avelumab was approved in the United States, the EU, and many countries in 2017 as a concentrate for the preparation of an infusion solution (Bavencio). Structure and properties Avelumab is a human IgG1λ monoclonal antibody against programmed cell death ligand 1 (PD-L1) with a molecular weight of 147 kDa. It is produced by biotechnological … Avelumab
