Products Lapatinib is commercially available in the form of film-coated tablets (Tyverb). It has been approved in many countries since 2007. Structure and properties Lapatinib (C29H26ClFN4O4S, Mr = 581.1 g/mol) is present in drugs as lapatinibditosylate monohydrate. It is a 4-aniline quinazoline that exists as a yellow powder that is sparingly soluble in water. Effects … Lapatinib
Products Larotrectinib has been approved in the United States since 2018, in the EU since 2019, and in many countries since 2020 in capsule and oral solution form (Vitrakvi). Structure and properties Larotrectinib (C21H22F2N6O2, Mr = 428.4 g/mol) is present in the drug as larotrectinib sulfate. Effects Larotrectinib (ATC L01XE53) has antitumor and antiproliferative properties. … Larotrectinib
Products Idelalisib was approved in many countries in 2015 in film-coated tablet form (Zydelig). Structure and properties Idelalisib (C22H18FN7O, Mr = 415.4 g/mol) exists as a white powder that is soluble in acidic environments. Effects Idelalisib (ATC L01XX47) has antiproliferative, selective cytotoxic, and antitumor properties. The effects are due to inhibition of phosphatidylinositol 3-kinase p110δ. … Idelalisib
Products Ramucirumab is commercially available as a concentrate for the preparation of an infusion solution (Cyramza). It was approved in many countries in 2015. Structure and properties Ramucirumab is a human IgG1 monoclonal antibody with a molecular mass of 147 kDa that binds to the extracellular domain of VEGFR-2. Ramucirumab is produced by biotechnological methods. … Ramucirumab
Products Wasabi is commercially available as a spice powder (wasabi powder), as wasabi paste, and as a snack (e.g., peanuts, potato chips), among other products. The plant itself can also be purchased. The quality of the products is often low. Where it says wasabi, it often contains very little spice. To fake or enhance the … Wasabi
Products Commercially available products include rosehip teas, tea blends with rosehips, fruit teas, cold teas, rosehip jam, the medicinal drug and rosehip powder. The deep red color of rosehip tea does not come from the rose hips at all, but from the hibiscus flowers, which are usually additionally contained in the tea. Rosehip tea as … Rosehip
Products Imiquimod is commercially available as a cream in single-use sachets (Aldara 5%). It has been approved in many countries since 1999. Since 2014, a preparation containing 3.75% imiquimod has also been registered in many countries (Zyclara). Structure and properties Imiquimod (C14H16N4, Mr = 240.3 g/mol) is an imidazoquinoline amine structurally similar to nucleoside analogs … Imiquimod: Drug Effects, Side Effects, Dosage and Uses
Products Ribociclib was approved in the United States, the EU, and many countries in 2017 in film-coated tablet form (Kisqali). Structure and properties Ribociclib (C23H30N8O, Mr = 434.5 g/mol) is present in the drug as ribociclibsuccinate, a pale yellow to yellow-brown crystalline powder. Effects Ribociclib (ATC L01XE42) has antitumor and antiproliferative properties. The effects are … Ribociclib
Products Binimetinib was approved in the EU and US in 2018 and in many countries in 2019 in film-coated tablet form (Mektovi). Structure and properties Binimetinib (C17H15BrF2N4O3, Mr = 441.2 g/mol) exists as a light yellow powder that is practically insoluble in water. Effects Binimetinib (ATC L01XE41) has antitumor and antiproliferative properties. The effects are … Binimetinib
Products Atezolizumab was approved as an infusion product in the United States in 2016 and in the EU and many countries in 2017 (Tecentriq). Structure and properties Atezolizumab is a humanized IgG1κ monoclonal antibody with a molecular mass of 145 kDa. Effects Atezolizumab (ATC L01XC32) has immunostimulatory and antitumor properties. The effects are due to … Atezolizumab
Products Brentuximab vedotin is commercially available as a powder for the preparation of an infusion solution (Adcetris). It has been approved in many countries since 2013. Structure and properties Brentuximab vedotin is an anti-CD30 antibody-drug conjugate, a recombinant chimeric lgG1 antibody conjugated to the cytotoxic agent monomethylauristatin E (MMAE, C39H67N5O7, Mr = 718.0 g/mol). It … Brentuximab Vedotin
Products Oolong tea is available, for example, in pharmacies, drugstores and specialty tea stores. It originated in Fujian province in China and is now produced in various Asian countries. Stem plant The parent plant is the tea plant from the tea shrub family (Theaceae). It grows into an evergreen shrub or tree. Medicinal drug The … Oolong
