Products Valganciclovir is commercially available in the form of film-coated tablets (Valcyte). It has been approved in many countries since 2001. Generic versions were registered in 2014. Structure and properties Valganciclovir (C14H22N6O5, Mr = 354.4 g/mol) is an L-valine ester prodrug of ganciclovir and is present in the drug product as valganciclovir hydrochloride, a white … Valganciclovir
Products Dasabuvir is commercially available in the form of film-coated tablets. It was approved in many countries in 2014 (Exviera). Structure and properties Dasabuvir (C26H27N3O5S, Mr = 493.6 g/mol) has a non-nucleoside structure. It exists in the drug as a sodium salt and as a monohydrate. Effects Dasabuvir (ATC J05AX16) has antiviral properties. The effects … Dasabuvir
Products Ombitasvir was approved in the EU and many countries in 2014 in film-coated tablet form (Viekirax, combination drug). Structure and properties Ombitasvir (C50H67N7O8, Mr = 894.1 g/mol) Effects Ombitasvir (ATC J05AX66) has antiviral properties against HCV virus. The effects are due to binding to the viral protein NS5A (Non-Structural Protein 5A). Unlike other HCV … Ombitasvir
Products Direct antiviralia are commercially available as drugs in the form of tablets, capsules, solutions, and creams, among others. The first antiviral agent was approved in the 1960s (idoxuridine). Structure and properties Antivirala are a large group of drugs and have no uniform chemical structure. However, groups can be formed, such as the nucleoside analogs. … Antiviralia
Products Favipiravir is approved in Japan in the form of film-coated tablets (Avigan). Structure and properties Favipiravir (C5H4FN3O2, Mr = 157.1 g/mol) is a fluorinated pyrazine carboxamide derivative. It is a prodrug that is biotransformed in cells to the active metabolite favipiravir-RTP (favipiravir-ribofuranosyl-5′-triphosphate), a purine nucleotide analog. Favipiravir exists as a white to slightly yellow … Favipiravir
Products Penciclovir is commercially available as a cream and tinted cream (Fenivir). It has been approved in many countries since 1997. Famvir cream is out of commerce. Structure and properties Penciclovir (C10H15N5O3, Mr = 253.3 g/mol) is a mimetic of the DNA building block 2′-deoxyguanosine and is structurally related to aciclovir. It exists as a … Penciclovir
Products Oseltamivir is commercially available as capsules and as a powder for oral suspension (Tamiflu). It has been approved in many countries since 1999. Generics were first registered in the EU in 2014 (ebilfumin) and in many countries in 2018. Structure and properties Oseltamivir (C16H28N2O4, Mr = 312.4 g/mol) is present in drugs as oseltamivir … Oseltamivir
Symptoms Possible symptoms include vulvovaginal dryness, itching, inflammation, burning, feeling of pressure, discharge, light bleeding, pain during sexual intercourse, and local infectious disease. The urinary tract may be involved, manifested, for example, by frequent and painful urination, cystitis, blood in the urine, and urinary incontinence. Causes A common cause of symptoms is vaginal atrophy in … Vaginal Dryness: Causes and Treatment
Products Brivudine is commercially available in tablet form (Brivex). It has been approved in many countries since 2003. It was originally developed in the German Democratic Republic. Structure and properties Brivudine (C11H13BrN2O5, Mr = 333.1 g/mol) is a nucleoside analog related to thymidine. Effects Brivudine (ATC J05AB) has antiviral properties against herpes viruses. It inhibits … Brivudine
Products Trifluridine is commercially available in the form of eye drops and other products. This article relates to ocular therapy. Structure and properties Trifluridine (C10H11F3N2O5, Mr = 296.2 g/mol) is a fluorine derivative of thymidine and is therefore also known as trifluorothymidine. Effects Trifluridine (ATC S01AD02) has antiviral properties. It inhibits thymidic acid synthetase, viral … Trifluridine
Products Letermovir was approved in the United States in 2017 and in the EU and many countries in 2018 in tablet form and as an intravenous solution for injection (Prevymis). Structure and properties Letermovir (C29H28F4N4O4, Mr = 572.6 g/mol) Effects Letermovir (ATC J05AX18) has antiviral properties. The effects are due to inhibition of the CMV … Letermovir
Drug groups See under: Antibiotics – Bacterial Infectious Diseases Antifungals – Fungal Infections Antiparasitics – Parasitic Infectious Diseases Antiviralia – Viral Infectious Diseases.
