Golimumab

Products Golimumab is commercially available as a solution for injection (Simponi). It was approved in many countries in 2010. Structure and properties Golimumab (Mr = 150 kDa) is a human IgG1κ-monoclonal antibody. Effects Golimumab (ATC L04AB06) has selective immunosuppressive and anti-inflammatory properties. The effects are based on binding to the soluble and membrane-bound proinflammatory cytokine … Golimumab

Chemokines: Structure, Function & Diseases

Chemokines are small signaling proteins that trigger chemotaxis (migratory movement) of cells. In most cases, these cells are immune cells. Thus, chemokines are responsible for the effective functioning of the immune system. What are chemokines? Chemokines are small proteins that belong to the cytokine family. They cause cells to migrate. Mainly, these are immune cells … Chemokines: Structure, Function & Diseases

Chemosynoviorthesis: Treatment, Effects & Risks

Chemosynoviorthesis is the name given to a procedure used in the therapy of arthritic changes in the synovium (synovial membrane, joint mucosa) in inflammatory joint diseases. Analogous to radiosynoviorthesis (injection of radioactive substances), a chemical pharmaceutical is injected into the affected joint to obliterate the synovial membrane. What is chemosynoviorthesis? Chemosynoviorthesis represents a therapeutic procedure … Chemosynoviorthesis: Treatment, Effects & Risks

Chemotaxis: Function, Role & Diseases

Chemotaxis influences the direction of locomotion of cells and living organisms. Chemotaxis is based on a concentration gradient of substances, which can be represented by a substance concentration gradient. What is chemotaxis? Chemotaxis affects the direction of locomotion of cells and living organisms. The term chemotaxis refers to the influence of the locomotion of living … Chemotaxis: Function, Role & Diseases

Fat Loss: Function, Tasks, Role & Diseases

Fat breakdown, also called lipolysis, occurs mainly in fat cells (adipocytes). The most important function of lipolysis is energy production. However, there are interfering factors that inhibit fat breakdown. What is fat breakdown? Fat breakdown, also called lipolysis, occurs mainly in fat cells. The most important function of lipolysis is energy production. Fat breakdown in … Fat Loss: Function, Tasks, Role & Diseases

Balneology: Treatment, Effect & Risks

Balneology is the science of baths. Balneological procedures take place mainly in the context of spa treatments. Respiratory diseases and skin diseases can be alleviated by balneological treatments, as well as metabolic diseases and various symptoms of nervous system diseases. What is balneology? Balneology is the science of baths. Balneological procedures take place primarily as … Balneology: Treatment, Effect & Risks