Omeprazole: Effects, Uses & Risks

Diseases such as gastritis, peptic ulcer, or the use of medications that are harmful to the stomach may require the use of a stomach-protecting, acid-inhibiting agent. Modern medicine has a number of appropriate drugs available that work effectively and gently. One of the most commonly prescribed agents is omeprazole. What is omeprazole? The active ingredient … Omeprazole: Effects, Uses & Risks

Cobicistat

Products Cobicistat is commercially available as a monopreparation (Tybost) and as a fixed combination with elvitegravir, emtricitabine, and tenofovirdisoproxil in the form of film-coated tablets (Stribild). It has been approved in many countries since 2013. Other combination products exist with darunavir (Rezolsta) and with atazanavir (Evotaz). Structure and properties Cobicistat (C40H53N7O5S2, Mr = 776.0 g/mol) … Cobicistat

Omeprazole: Drug Effects, Side Effects, Dosage and Uses

Products Omeprazole is commercially available in tablet, capsule, and injection/infusion forms and has been approved in many countries since 1988. In addition to the original Antramups, generics and the -enantiomer esomeprazole (Nexium) are also commercially available. At the end of March 2010, after pantoprazole, omeprazole was also approved for self-medication in many countries. In the … Omeprazole: Drug Effects, Side Effects, Dosage and Uses

Pantoprazole

Products Pantoprazole is commercially available in the form of enteric-coated tablets and has been approved in many countries since 1997 (Pantozol, generic). Less commonly used are the granules and the injectable. Structure and properties Pantoprazole (C16H15F2N3O4S, Mr = 383.37 g/mol) is a benzimidazole derivative and a racemate. In tablets, it is present as sodium salt … Pantoprazole

Raltegravir

Products Raltegravir is commercially available as film-coated tablets and chewable tablets (Isentress). It was approved in the United States in 2007 and in many countries in 2008 as the first integrase inhibitor. Structure and properties Raltegravir (C20H21FN6O5, Mr = 444.4 g/mol) is a hydroxypyrimidinone carboxamide. It is present in drugs in the form of the … Raltegravir

HIV Protease Inhibitor

Products Most HIV protease inhibitors are commercially available in tablet or capsule form. In addition, a few liquid dosage forms are available for ingestion. Saquinavir (Invirase) was the first to be lanicized in 1995. Structure and properties The first HIV protease inhibitors were modeled on the natural peptide substrate of the HIV protease. The protease … HIV Protease Inhibitor

Atazanavir: Effects, Uses & Risks

Atazanavir is an active medical substance. It is used to treat HIV infection. What is atazanavir? Atazanavir is a medical active ingredient. It is used for the therapy of HIV infections. The drug atazanavir is commercially available in Germany under the name Reyataz. It is taken orally and is used to treat HIV infections. The … Atazanavir: Effects, Uses & Risks

Dexlansoprazole

Products Dexlansoprazole was approved in many countries in 2014 in the form of modified-release capsules (Dexilant). Generic versions were registered in 2020. Structure and properties Dexlansoprazole (C16H14F3N3O2S, Mr = 369.4 g/mol) is the pure -enantiomer of the racetmate lansoprazole (Agopton, both Takeda; generics). It exists as a white crystalline powder that is sparingly soluble in … Dexlansoprazole

Atazanavir

Products Atazanavir is commercially available in capsule form (Reyataz). It has been approved in many countries since 2004. Generic versions were registered in 2017. Structure and properties Atazanavir (C38H52N6O7, Mr = 704.9 g/mol) is present in drugs as atazanavir sulfate, a white to slightly yellow crystalline powder that is sparingly soluble in water. Effects Atazanavir … Atazanavir

Meulengracht’s Disease

Background The human organism has several mechanisms to metabolize endogenous and foreign substances. One of these mechanisms is glucuronidation, which occurs primarily in the liver. In this process, enzymes from the superfamily of UDP-glucuronosyltransferases (UGT) transfer a molecule of glucuronic acid from UDP-glucuronic acid to the substrate. Using acetaminophen as an example, alcohols, phenols, carboxylic … Meulengracht’s Disease

Lansoprazole

Products Lansoprazole is commercially available in the form of capsules as meltable tablets (Agopton, generics). It has been approved in many countries since 1993. Structure and properties Lansoprazole (C16H14F3N3O2S, Mr = 369.4 g/mol) is a benzimidazole and pyridine derivative. It exists as a white to brownish-white, odorless, crystalline powder that is practically insoluble in water. … Lansoprazole

Rifampicin: Effects, Uses & Risks

Rifampicin is the name given to an antibiotic. It comes from the fungal species Streptomyces mediterranei. What is rifampicin? Rifampicin is one of the antibiotics and belongs to the group of rifamycins. It can be used against different types of bacteria. Rifampicin is one of the antibiotics and belongs to the group of rifamycins. It … Rifampicin: Effects, Uses & Risks