Baclofen: Effects, Applications, Side Effects

How baclofen works Baclofen attacks a specific docking site of the nerve messenger gamma-aminobutyric acid (GABA) – the GABA-B receptor. The active ingredient thus mimics the effect of GABA and activates the receptors. These are specifically responsible for muscle tension. This results in a relaxation of the affected muscles – existing spasticity is alleviated. GABA … Baclofen: Effects, Applications, Side Effects

Neurodegeneration with Iron Deposition in the Brain: Causes, Symptoms & Treatment

Neurodegeneration with iron deposition in the brain represents a disease that occurs with a very low frequency. The disease is also often referred to by the abbreviation NBIA in international medical jargon. Neurodegeneration with iron deposition in the brain leads to neurological degeneration. A typical feature of the disease is primarily that iron is deposited … Neurodegeneration with Iron Deposition in the Brain: Causes, Symptoms & Treatment

Memantine

Products Memantine is commercially available as film-coated tablets, meltable tablets, and oral solution (Axura, Ebixa). It has been approved in many countries since 2003. Generic versions were registered in 2014. Structure and properties Memantine (C12H21N, Mr = 179.3 g/mol) is present in drugs as memantine hydrochloride, a white powder that is insoluble in water. Memantine … Memantine

Pain Pump: Applications & Health Benefits

A pain pump allows patients to self-administer a specific dose of pain medication. Known as ‘patient-controlled analgesia,’ pain and palliative care physicians use the procedure as part of specific therapy. What is a pain pump? A pain pump allows patients to self-administer a specific dose of pain medication. A patient-controlled pain pump continuously delivers medication … Pain Pump: Applications & Health Benefits

Baclofen

Products Baclofen is commercially available as in tablet form and as a solution for injection (Lioresal, generics). It has been approved in many countries since 1970. Structure and properties Baclofen (C 10 H 12 ClNO 2 , M r = 213.7 g/mol) exists as a white and odorless powder that is sparingly soluble in water. … Baclofen

Gabapentin: Drug Effects, Side Effects, Dosage and Uses

Products Gabapentin is commercially available in the form of capsules and film-coated tablets (Neurontin, generic). It has been approved in many countries since 1994. Pfizer launched pregabalin (Lyrica) as its successor in 2004. Structure and properties Gabapentin (C 9 H 17 NO 2 , M r = 171.2 g/mol) is structurally a GABA analog and … Gabapentin: Drug Effects, Side Effects, Dosage and Uses

Urinary Incontinence: Causes and Treatment

Symptoms Urinary incontinence manifests as involuntary leakage of urine. The common problem poses a psychosocial challenge for those affected, which can lead to changes in personal activities and a loss of quality of life. Risk factors include female gender, age, obesity, and numerous medical conditions. Causes Urinary incontinence can occur as a result of pathologic, … Urinary Incontinence: Causes and Treatment

Ziconotide: Effects, Uses & Risks

Ziconotide is the name given to an analgesic. The drug is used to treat severe chronic pain. What is ziconotide? Ziconotide is the name given to an analgesic. The drug is used to treat severe chronic pain. Ziconotide is administered with the help of an intrathecal catheter. The active ingredient ziconotide is a polypeptide used … Ziconotide: Effects, Uses & Risks

Baclofen: Effects, Uses & Risks

Baclofen was originally developed in the 1960s to treat epilepsy. It has a good effect on spastic seizures. Since 2009, it has also been used to combat alcohol addiction. What is baclofen? Baclofen was originally developed in the 1960s to treat epilepsy. Since 2009, it has also been used to combat alcohol addiction. Baclofen – … Baclofen: Effects, Uses & Risks