Silymarin (Milk Thistle Fruit Extract): Definition, Metabolism, Bioavailability

Silymarin is a fruit extract and comes from milk thistle (Silybum marianum). This medicinal plant belongs to the composite family (Asteraceae), subfamily Carduoideae. With a stem height of 20 cm to 150 cm, the annual to biennial herb is easily recognizable by its white-green marbled leaves and purple flower. Milk thistle grows preferentially on dry, … Silymarin (Milk Thistle Fruit Extract): Definition, Metabolism, Bioavailability

Silymarin (Milk Thistle Fruit Extract): Functions

Traditionally, silymarin has been used as a tea or dry extract to treat diseases of the liver, gallbladder, and spleen. It is now one of the best-studied phytochemicals.Based on clinical data, silymarin is used supportively for the following conditions: Alcohol-related liver disease Cirrhosis of the liver Acute and chronic hepatitis Liver disease induced by drugs, … Silymarin (Milk Thistle Fruit Extract): Functions

Rose Root (Rhodiola Rosea): Functions

Rhodiola rosea is one of the herbal adaptogens according to the European Medicines Agency (EMA). According to initial studies, the physiologically active substances, such as rosavins, support the organism in stressful situations and increase stress resistance. The immune system is adapted to stress, so that the organism is better able to cope with extraordinary stress. … Rose Root (Rhodiola Rosea): Functions

Rose Root (Rhodiola Rosea): Interactions

In vitro studies demonstrate that constituents of rose root extract have inhibitory effects on various enzyme activities (e.g., CYP3A4, CYP19). CYP3A4 is used to metabolize (metabolize) drugs and CYP19 catalyzes estrogen synthesis. Interactions with drugs and food are possible, but have not been observed in animal or human studies to date. Therefore, due to the … Rose Root (Rhodiola Rosea): Interactions

Rose Root (Rhodiola Rosea): Safety Assessment

The German Federal Institute for Risk Assessment (BfR) has conducted a risk assessment for Rhodiola rosea and concluded that there is no hazard potential at daily doses of 100-1,800 mg of rose root (mostly as root extract) Rose root contains, among other substances, the cyanogenic glycoside lotaustralin. When the plant is injured, cyanides (salts of … Rose Root (Rhodiola Rosea): Safety Assessment

Phospholipids

Phospholipids, also called phosphatides, are present in every cell of the human body and belong to the membrane lipid family. They form the main component of the lipid bilayer of a biomembrane, such as the cell membrane. In the myelin membrane of Schwann’s cells, which surround the axons of nerve cells, the phospholipid content is … Phospholipids

Probiotics: Definition, Transport and Distribution

Various definitions currently exist for the term probiotics (Greek pro bios – for life). According to the definition by Fuller 1989, a probiotic is “a preparation of living microorganisms which, after oral application, influences the ratio of intestinal germs in such a way that positive effects on the organism result.” At the European level, the … Probiotics: Definition, Transport and Distribution

Probiotics: Functions

With the experimental and clinical studies currently available, it can be demonstrated that probiotics are capable of the following beneficial effects: Promotion or maintenance of optimal intestinal flora. Prevention of colonization of pathogenic germs in the intestine and the passage of pathogenic bacteria through the intestinal wall (translocation). Formation of the short-chain fatty acid butyrate, … Probiotics: Functions

Probiotics: Food

Intake recommendations of the German Nutrition Society (DGE) are not yet available for probiotics. Foods containing strains of bacteria with probiotic activity, such as lactic acid bacteria (lactobacilli). Acidified milk products Tilsit Fermented vegetables Acidified milk/soured milk Mountain cheese Sour cucumbers Buttermilk Cheddar Sauerkraut Sour cream Brie Beet Yogurt Camembert Green beans (lactic acid fermented) … Probiotics: Food