Bendamustine: Effects, Uses, Side Effects

How Bendamustine works Bendamustine is an active ingredient used in cancer therapy – more precisely, in chemotherapy. As a representative of the alkylating cytostatic drugs, the active ingredient combats tumor cells by irreversibly changing the molecular structure of their genetic material (DNA). The cells can then no longer divide and multiply. As a result, they … Bendamustine: Effects, Uses, Side Effects

Bendamustine

Products Bendamustine is commercially available as a lyophilizate for the preparation of an infusion solution (ribomustine). It actually has good oral bioavailability when taken fasting, but is only administered parenterally. Generic drugs are registered. Bendamustine was developed in 1963 by Ozegowski et al. in Jena in what was then East Germany and was marketed only … Bendamustine

Bendamustine: Effects, Uses & Risks

Bendamustine is a highly effective chemotherapeutic agent that achieves better treatment results in certain types of cancer compared with conventional therapies (CHOP regimens). At the same time, it is associated with significantly fewer side effects than these. Most patients rate the hair loss, which occurs only rarely, as particularly positive. What is bendamustine Bendamustine is … Bendamustine: Effects, Uses & Risks

Rituximab: Effects, Uses & Risks

Rituximab is a drug in the cytostatic drug class. It is a monoclonal antibody used primarily in the treatment of malignant lymphoma. What is rituximab? Rituximab was developed in the 1990s by Lee Nadler at Dana-Farber Cancer Institute. It was the first antibody approved for the treatment of cancer worldwide. In the EU, rituximab is … Rituximab: Effects, Uses & Risks