Prolongation of the QT Interval

Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval

Decongestants: Effect, Uses & Risks

Decongestants are drugs that exert a decongestant effect and are used as supportive agents in the treatment of allergic diseases. They are not a uniform group of active substances. The individual substances act according to different mechanisms but with the same result of mucosal decongestion in each case. What are decongestants? Decongestants are drugs that … Decongestants: Effect, Uses & Risks

Bilirubin: Structure, Function & Diseases

Bilirubin is a breakdown product in hemoglobin metabolism. Macrophages continuously break down old erythrocytes in the liver and spleen to generate bilirubin. If this process is disturbed, the substance accumulates and jaundice develops. What is bilirubin? Bilirubin is the breakdown product of red blood pigment. This pigment is also known as hemoglobin. Red blood cells … Bilirubin: Structure, Function & Diseases

Hyperemia: Causes, Symptoms & Treatment

When a noticeable amount of blood is gathered in any part of the body and redness with swelling develops, it is called hyperemia. Often, a blood vessel has dilated due to irritation, an insect bite, or inflammation. Hyperemia can also be produced artificially. What is hyperemia? The definition of hyperemia is consequently: As opposed to … Hyperemia: Causes, Symptoms & Treatment

Calcitriol: Function & Diseases

Calcitriol is a very potent secosteroid that resembles steroid hormones because of its structure. It is hydroxylated in a wide variety of tissues, but predominantly in the kidneys, and is sometimes prescribed as a medication. What is calcitriol? Unlike other vitamins, vitamin D can be produced in the body itself. Deficiency symptoms only occur when … Calcitriol: Function & Diseases

Dexmedetomidine

Products Dexmedetomidine is commercially available as a concentrate for the preparation of an infusion solution (Dexdor). It was approved in many countries in 2012. Structure and properties Dexmedetomidine (C13H16N2, Mr = 200.3 g/mol) is an imidazole derivative and the -enantiomer of medetomidine. It is structurally closely related to detomidine and is present in drugs as … Dexmedetomidine