Sorivudine is a medical drug that was developed in Japan to treat herpes. Sorivudine was marketed under the trade name Usevir and has been unavailable since a drug scandal killed several people in Japan. It did not even receive approval in Europe, so the drug did not have to be withdrawn from the market. What … Sorivudine: Effects, Uses & Risks
Products 5-Fluorouracil is commercially available as an ointment (Efudix), as a topical solution in combination with salicylic acid (Verrumal), and in preparations for parenteral administration. This article refers to topical application. In 2011, 5-fluorouracil at the lower concentration of 0.5% was approved in many countries with Actikerall. Structure and properties 5-Fluorouracil (C4H3FN2O2, Mr = 130.08 … 5-Fluorouracil
Symptoms After the initial clinical manifestation in the form of chickenpox, the virus remains in a latent stage in the dorsal root ganglia for life. Reactivation of the virus occurs particularly in the presence of weakened immune defenses. Vesicles with cloudy contents form in the area supplied by the infected nerve, e.g. on the trunk … Shingles: Causes, Symptoms, Treatment, Prevention
Radiculopathy refers to damage or irritation of the nerve roots. This results in pain, sensory disturbances or paralysis. What is radiculopathy? Radiculopathy is also known as radiculitis, root syndrome or root neuritis. It refers to damage to the nerve root, which can take either an acute or chronic course. It is accompanied by pain, sensory … Radiculopathy: Causes, Symptoms & Treatment
Products Capecitabine is commercially available in the form of film-coated tablets (Xeloda, generic). It has been approved in many countries since 1998. Structure and properties Capecitabine (C15H22FN3O6, Mr = 359.4 g/mol) is a prodrug and is converted to the cell-toxic 5-fluorouracil, the active drug, in a three-step process. Capecitabine exists as a white crystalline powder … Capecitabine
Products Brivudine is commercially available in tablet form (Brivex). It has been approved in many countries since 2003. It was originally developed in the German Democratic Republic. Structure and properties Brivudine (C11H13BrN2O5, Mr = 333.1 g/mol) is a nucleoside analog related to thymidine. Effects Brivudine (ATC J05AB) has antiviral properties against herpes viruses. It inhibits … Brivudine
Brivudine is a nucleoside analog used as a virostatic agent for herpes simplex type 1 and herpes zoster infections. It is the drug of choice for these indications in patients older than 50 years. What is brivudine? Brivudine is a substance from the group of nucleoside analogues and is used for herpes simplex type 1 … Brivudine: Effects, Uses & Risks
What are prodrugs? Not all active pharmaceutical ingredients are directly active. Some must first be converted to the active substance by an enzymatic or non-enzymatic conversion step in the body. These are the so-called . The term was introduced by Adrien Albert in 1958. It is estimated that up to 10% of all active ingredients … Prodrugs
Zoster oticus is a secondary disease with the varicella-zoster virus. In this case, the symptoms appear in the ear region. What is zoster oticus? Zoster oticus represents a special form of shingles (herpes zoster). It refers to an infectious disease in the course of which inactive herpes viruses become active again in the ganglia of … Zoster Oticus: Causes, Symptoms & Treatment
What is Brivudin? Brivudine is the active ingredient in drugs used to treat specific diseases caused by herpes viruses. It is a nucleoside analogue and is much more effective than similar antiviral drugs. Nucleoside analogues have a structural similarity with the building blocks of DNA. If a nucleoside analogue is inserted instead of the actual … Brivudin
How does Brivudin work? Brivudine is a so-called nucleoside analogue. Nucleosides belong to the building blocks of the DNA of our cells. If brivudine is used instead of a normal nucleoside in the DNA structure, the further re-synthesis of the genetic information stops. The effect of brivudine is therefore that it interferes with the reproduction … How does Brivudin work? | Brivudin
When should Brivudin not be given? Brivudine must not be given to certain groups of patients: Therefore, it is imperative that the treating physician be informed of all medications that are taken regularly. – during pregnancy and lactation If the patient is younger than 18 years In case of known hypersensitivity to brivudine and the … When should Brivudin not be given? | Brivudin
