Products The first therapeutic monoclonal antibody was approved in 1986. Muromonab-CD3 (Orthoclone OKT3) binds to the CD3 receptor on T cells and has been used in transplantation medicine. Numerous drugs containing antibodies are now available. A selection of active substances can be found at the end of this article. These are expensive drugs. For example, … Monoclonal Antibodies
Products Canakinumab is commercially available as a powder for solution for injection (Ilaris). It has been approved in many countries since 2009. Structure and properties Canakinumab is a recombinant human IgG1κ monoclonal antibody produced by biotechnological methods. Effects Canakinumab (ATC L04AC08) has anti-inflammatory properties. The effects are based on binding to interleukin-1β (IL-1β). This reduces … Canakinumab
