Products Azelastine is available as a nasal spray and in eye drop form (eg, Allergodil, Dymista + fluticasone, generics). It has been approved in many countries since 1994. Structure and properties Azelastine (C22H24ClN3O, Mr = 381.9 g/mol) is present in drugs as azelastine hydrochloride, a white to almost white crystalline powder. It is a phthalazinone … Azelastine
Products Benfluorex was marketed in many countries as Mediaxal (150 mg, Servier) until 1998. Today, it is no longer on the market. In France and other European countries, it was available as Mediator, among other products. Its approval was not withdrawn in France until 2009, although the risk for cardiotoxic side effects of comparable drugs … Benfluorex
Products Preparations of aconite are mainly found in homeopathic, anthroposophic and other alternative medicines. Various dosage forms are available, such as globules, oils, drops, ear drops and ampoules. Stem plant Blue monkshood L. from the Ranunculaceae family is native to the Alps, among other places. The photos were taken in the botanical garden Brüglingen, in … Blue Monkshood
Products Antihistamines are often taken in the form of tablets. In addition, drops, solutions, lozenges, capsules, gels, creams, eye drops, nasal sprays, and injectable solutions are also available, among others. The first active ingredient from this group was phenbenzamine (Antergan), developed in France in the 1940s. It is no longer commercially available today. Structure and … Antihistamines for Allergies
Products Fexofenadine is commercially available in tablet form (Telfast, Telfastin Allergo, generic). It was approved in many countries in 1997 and has been available without a doctor’s prescription since 2010. Telfastin Allergo 120 for self-medication went on sale in February 2011. Fexofenadine is the successor product to terfenadine (Teldane), which had to be withdrawn from … Fexofenadine
Products Loratadine is commercially available in tablet form (Claritine, Claritine Pollen, generics). It has been approved in many countries since 1991. The active metabolite desloratadine is also available (Aerius, generics). Structure and properties Loratadine (C22H23ClN2O2, Mr = 382.9 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug … Loratadine
Products Uzara extracts have been used in Germany since the year 1911 and are now commercially available in the form of tablets, as a solution and juice for oral use (Uzara). The products are obtained by dry extraction from the root of the Uzara plant of the Asclepiadoideae family, which is native to South Africa … Uzara Root
Products Terfenadine (Teldane tablets/suspension) is no longer on the market in many countries. Possible alternatives are the successor product fexofenadine (Telfast) or other 2nd generation antihistamines. Structure and properties Terfenadine (C32H41NO2, Mr = 471.7 g/mol) is a racemate. It exists as a white crystalline powder that is very sparingly soluble in water. Terfenadine is a … Terfenadine
Products Ribavirin is commercially available in the form of film-coated tablets (Copegus). It has been approved in many countries since 1990. Structure and properties Ribavirin (C8H12N4O5, Mr = 244.2 g/mol) is a purine nucleoside analog. It exists as a white crystalline powder that is readily soluble in water. In cells, the drug is biotransformed to … Ribavirin
