clarithromycin

Clarithromycin: effects, indications, side effects

How clarithromycin works Clarithromycin penetrates the bacterial cells and prevents them from producing vital proteins. The bacteria are therefore not killed by the antibiotic, but their growth is inhibited. The active ingredient has a bacteriostatic effect. This inhibition of bacterial growth gives the immune system the opportunity to contain the infection. Compared to erythromycin, another … Clarithromycin: effects, indications, side effects

Cat Scratch Disease

Symptoms Classic cat scratch disease first manifests as a red papule or pustule at the site where the cat scratched or bit. Soon, local lymphadenitis (inflammation and swelling of the lymph nodes) occurs on the side of the body with the injury, often on the armpit or neck. Children and adolescents are particularly affected. Other … Cat Scratch Disease

Prolongation of the QT Interval

Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval

Erythromycin: Effects, Uses & Risks

Erythromycin is an antibiotic and is used to prevent or treat bacterial infections. It can be used on the skin, externally, or orally, internally. Erythromycin is subject to medical prescription in Germany, so it is not available over-the-counter in pharmacies. What is erythromycin? Erythromycin is an antibiotic and is subject to medical prescription in Germany, … Erythromycin: Effects, Uses & Risks

Simvastatin: Effects, Uses & Risks

Simvastatin is a classic statin and is used as a cholesterol-lowering agent. It was approved in 1990 and is used relatively frequently. What is simvastatin? Simvastatin, chemically (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl-2,2-dimethylbutanoate, is a drug used primarily as a cholesterol-lowering agent. Simvastatin is structurally derived from the naturally occurring monacolin K, also known as lovastatin. Simvastatin is partially synthetically … Simvastatin: Effects, Uses & Risks

Colchicine

Products Medicines containing colchicine are no longer on the market in many countries. Drugs are available abroad that can be imported. It may also be possible to prepare an extemporaneous formulation in a pharmacy (difficulties: toxicity, substance). Stem plant Colchicine is the main alkaloid of the autumn crocus (Colchicaceae), which contains it particularly abundantly in … Colchicine

Lyme Diseases: Causes and Treatment

Symptoms The disease has traditionally been divided into 3 stages, which, however, cannot be clearly distinguished from each other and do not require patients to pass through them obligatorily and sequentially. The staging has therefore been abandoned by some experts in favor of an early and late phase or organ-based classification. Borrelia initially infect the … Lyme Diseases: Causes and Treatment

Cytochrome P450 (CYP)

CYP450 Cytochromes P450s are a family of enzymes that are of paramount importance in drug biotransformation. The most important isoenzymes for drug metabolism are: CYP1A1, CYP1A2 CYP2B6 CYP2C9, CYP2C19 CYP2D6 CYP2E1 CYP3A4, CYP3A5 and CYP3A7 The number after the abbreviation CYP stands for the family, the following letter for the subfamily and the last number … Cytochrome P450 (CYP)

Saquinavir: Effects, Uses & Risks

The active ingredient saquinavir is a protease inhibitor. The drug is primarily used for the therapy of HIV infections. In this context, the substance saquinavir is mainly used in combination preparations. The drug was approved in 1995. Since a large number of patients quickly developed resistance to the drug, saquinavir was taken off the pharmaceutical … Saquinavir: Effects, Uses & Risks

Interactions

Definition When two or more drugs are combined, they may affect each other. This is especially true with regard to their pharmacokinetics (ADME) and effects and adverse effects (pharmacodynamics). This phenomenon is called interaction and drug-drug interaction. Interactions are usually undesirable because they can lead to, for example, loss of efficacy, side effects, poisoning, hospitalization, … Interactions

Antibiotics: Antibacterial Drugs

Products Antibiotics (singular: antibiotic) are commercially available in the form of tablets, dispersible tablets, capsules, as infusion preparations, suspensions and syrups for children, and as granules, among others. There are also some topical preparations, such as creams, ointments, eye drops, eye ointments, ear drops, nasal ointments and sore throat tablets. The first active ingredient from … Antibiotics: Antibacterial Drugs

Antibiotic Suspensions for Children

Procedure in the pharmacy Refer to the package insert for each drug. 1. If the suspension is needed immediately, it is prepared by the pharmacist. If this is not desired, it can also be prepared by the parents. General instructions (example!): Shake the bottle with the powder to loosen the powder. Carefully fill with tap … Antibiotic Suspensions for Children