Atorvastatin

Products Atorvastatin is commercially available in the form of film-coated tablets (Sortis, generic, auto-generic). It has been approved in many countries since 1997. Atorvastatin is also available as a fixed combination with ezetimibe; see Atorvastatin and Ezetimibe. Structure and Properties Atorvastatin (C33H35FN2O5, Mr = 558.64 g/mol) is present in drugs as atorvastatin calcium trihydrate, (atorvastatin)2– … Atorvastatin

Ketoconazole: Effects, Uses & Risks

Ketoconazole is the name given to a medicinal substance that is used to treat fungal diseases on the skin. In addition, the substance is used in anti-dandruff shampoos. What is ketoconazole? Ketoconazole can slow the growth of filamentous fungi such as dermatophytes and yeast fungi such as Candida albicans. Ketoconazole is one of the drugs … Ketoconazole: Effects, Uses & Risks

Acute Otitis Media

Symptoms Acute otitis media is inflammation of the middle ear with local or systemic signs of inflammation and pus formation (fluid accumulation in the middle ear). It occurs primarily in infants and young children. Possible symptoms include: Earache Increased temperature, fever Hearing disorders Feeling of pressure Irritability, crying Digestive disorders: Lack of appetite, abdominal pain, … Acute Otitis Media

Repaglinide: Effects, Uses & Risks

Repaglinide is an active substance, which is used in the disease diabetes mellitus type 2, when dietary measures, weight reduction and physical training do not sufficiently reduce blood sugar. By inhibiting the potassium channels of the beta cells in the pancreas, the drug leads to the release of insulin. If the dosage and intake conditions … Repaglinide: Effects, Uses & Risks

Macrolides: Drug Effects, Side Effects, Dosage and Uses

Products Available dosage forms include tablets, powders and granules for the preparation of oral suspensions, injectables, and topical medications. Erythromycin was the first active ingredient from this group to be discovered in the 1950s. Structure and properties Erythromycin is a natural substance produced by the bacterium (formerly: ). Other agents such as clarithromycin are derived … Macrolides: Drug Effects, Side Effects, Dosage and Uses

P-Glycoprotein

P-glycoprotein P-glycoprotein (P-gp, MDR1) is a primary active efflux transporter with a molecular weight of 170 kDa, belonging to the ABC superfamily and consisting of 1280 amino acids. P-gp is the product of the -gene (formerly: ). P is for , ABC is for . Occurrence P-glycoprotein is found on various tissues of the human … P-Glycoprotein

Macrolide Antibiotics: Effects, Uses & Risks

Macrolide antibiotics are antibiotics that are bacteriostatic and have a macrolide. They inhibit the protein biosynthesis of bacteria. The first and best known macrolide antibiotic is erythromycin. Macrolide antibiotics are often used in children. What are macrolide antibiotics? Macrolide antibiotics (abbreviated as macrolides) are antibiotics with bacteriostatic activity. They represent a separate “classification” within the … Macrolide Antibiotics: Effects, Uses & Risks

Clarithromycin

Products Clarithromycin is commercially available as film-coated tablets, sustained-release tablets, oral suspension, and powder for solution for infusion (Klacid, generics). It has been approved in many countries since 1990. Clarithromycin should not be confused with ciprofloxacin. Structure and properties Clarithromycin (C38H69NO13, Mr = 747.96 g/mol) exists as a white crystalline powder that is practically insoluble … Clarithromycin

Pseudomycosis: Causes, Symptoms & Treatment

Pseudomycoses present the clinical picture of mycoses. However, unlike mycosis, pseudomycosis is not based on a fungal infection but on a bacterial infection. Therapy depends on the causative agent and the pattern of infestation but usually encompasses antibiotic administration. What is pseudomycosis? Mycoses are associated with microorganisms. They are fungal diseases that correspond to an … Pseudomycosis: Causes, Symptoms & Treatment