Heparin-induced thrombocytopenia (HIT)

Definition A decrease in the number of platelets due to the administration of heparin is called heparin-induced thrombocytopenia (HIT). A distinction is made between two forms, the non-immunological form (HIT type I) and the antibody induced form (HIT type II). Introduction The word thrombocytopenia refers to a deficiency of thrombocytes, i.e. blood platelets. The word … Heparin-induced thrombocytopenia (HIT)

Causes | Heparin-induced thrombocytopenia (HIT)

Causes Heparin-induced thrombocytopenia are either formed as a non-immunological, harmless early form (type I) or are based on the formation of antibodies against platelet factor 4/heparin complex (type II). These cause the blood to clump together and the platelets are, so to speak, “caught away” or “trapped”, they can no longer perform their natural function.Unfractionated … Causes | Heparin-induced thrombocytopenia (HIT)

Therapy | Heparin-induced thrombocytopenia (HIT)

Therapy The most important step in therapy is the immediate discontinuation of heparin if type II HIT is suspected. Also all other drugs containing heparin must not be used any further to prevent possible complications. These include ointments or catheter irrigations containing heparin. The anticoagulant therapy must be changed to non-heparin-based substances in order to … Therapy | Heparin-induced thrombocytopenia (HIT)

Clexane® during pregnancy

Clexane® is the trade name of a drug with the active ingredient enoxaparin. This belongs to the group of low-molecular-weight heparins and is intended to inhibit blood coagulation by inhibiting the activity of a coagulation factor (factor Xa). Clexane® is used for the prophylaxis of thromboses, the treatment of thrombosis and pulmonary embolism and for … Clexane® during pregnancy

What are the side effects? | Clexane® during pregnancy

What are the side effects? The side effects of Clexane® correspond to the general side effects of the preparation. In addition there are a few special features that should be considered. If the risk-benefit ratio has been weighed well, the side effects are minor. A great advantage is that Clexane® does not cross the placental … What are the side effects? | Clexane® during pregnancy

Thrombosis and pill | Thrombosis

Thrombosis and pill There are numerous factors that increase the risk of developing thrombosis. Especially the combination of different risk factors increases the risk. An important and frequent risk factor for women is the use of oral contraception, the so-called pill. Oral contraceptives are drugs taken mainly to prevent pregnancy and contain two active ingredients, … Thrombosis and pill | Thrombosis

Thrombosis

Synonyms in a broader sense Deep vein thrombosis (DVT) Phlebothrombosis Venous thrombosis Pelvic vein thrombosis Venous thrombosis Blood Clot Leg vein thrombosis Lower leg thrombosis Economy class syndrome Tourist Class Syndrome Airplane thrombosis Definition Thrombosis A thrombosis is the clotting of blood (formation of a clot) in the blood vessel system, which leads to a … Thrombosis

CausesRisk factors | Thrombosis

CausesRisk factors There are many risk factors that increase the risk of thrombosis. It is the combination of different risk factors that increases the risk in particular. As safe factors of risk are considered: Operations (especially artificial hip joint and artificial knee joint) Overweight Smoking Gender (Women > Men) Lack of exercise (long-distance flights= economy … CausesRisk factors | Thrombosis