How colchicine works Colchicine can effectively relieve the sometimes very severe pain of acute gout attacks. Gout is a metabolic disease in which the concentration of uric acid in the blood is elevated. If it exceeds a certain limit, some of the uric acid precipitates in the form of crystals and is deposited in the … Colchicine: Effect, Applications, Side Effects
Definition Pharmaceutical agents are excreted primarily in the urine and, via the liver, in the bile in the stool. When excreted via the bile, they re-enter the small intestine, where they may be reabsorbed. They are transported back to the liver via the portal vein. This repetitive process is called the enterohepatic circulation. It prolongs … Enterohepatic Circulation
Products Medicines containing colchicine are no longer on the market in many countries. Drugs are available abroad that can be imported. It may also be possible to prepare an extemporaneous formulation in a pharmacy (difficulties: toxicity, substance). Stem plant Colchicine is the main alkaloid of the autumn crocus (Colchicaceae), which contains it particularly abundantly in … Colchicine
The karyoplasm is the name given to the protoplasm within cell nuclei, which differs from the cytoplasm particularly in its electrolyte concentration. For DNA replication and transcription, the karyoplasm provides an optimal environment. In diabetic patients, nuclear inclusions of glycogen may be present in the karyoplasm. What is karyoplasm? Cell nuclei are located in the … Karyoplasm: Structure, Function & Diseases
The cytoplasm fills the interior of a human cell. It consists of the cytosol, a liquid or gel-like substance, the organelles (mitochondria, Golgi apparatus, and others), and the cytoskeleton. Overall, the cytoplasm serves enzymatic biosynthesis and catalysis as well as substance storage and intracellular transport. What is cytoplasm? The definition of cytoplasm is not uniform … Cytoplasm: Structure, Function & Diseases
Symptoms Gout is an inflammatory disease of the joints that manifests acutely in attacks of severe pain that worsens with pressure, touch, and movement. The joints are swollen with inflammation, and the skin is red and warm. Fever is observed. Gout often begins in the lower extremities and at the metatarsophalangeal joint (podagra). Urat crystals … Gout Causes and Treatment
Products Rosuvastatin is commercially available in the form of film-coated tablets (Crestor, generic, auto-generic). It was approved in many countries in 2006 (Netherlands: 2002, EU and US: 2003). The marketing authorization holder is AstraZeneca. The statin was originally developed at Shionogi in Japan. In the USA, generic versions came on the market in 2016. In … Rosuvastatin
Stem plant Colchicaceae, Autumn crocus. Medicinal drug Colchici semen – timothy seed: the dried seed of L. (Liliaceae) with a colchicine content of at least 0.5% (PH 4) – no longer officinal Colchici tuber – autumn crocus bulbs Colchici flos – autumn crocus flowers. Preparations Tinctura Colchici PH 5 Ingredients Tropolone alkaloids: colchicine Indications for … Autumn Crocus
The medical profession refers to hyper-IgD syndrome – also known as HIDS – as a hereditary disease that is predominantly characterized by recurrent episodes of fever. For this reason, hyper-IgD syndrome also belongs to the so-called periodic fever syndromes. During the fever episodes, the affected persons complain, among other things, of diarrhea, abdominal pain, and … Hyper IgD Syndrome: Causes, Symptoms & Treatment
Colchicine represents the longest known active ingredient for the therapy of acute gout attacks. The potent spindle poison is extracted from the tubers and seeds of the autumn crocus. What is colchicine? Colchicine represents the longest-known active ingredient for the treatment of acute gout attacks. Colchicine is the name given to a toxic active ingredient … Colchicine: Effects, Uses & Risks
Introduction Gout is a disease that is due to a malfunction of the purine metabolism and runs in waves. Patients suffering from gout should consult a physician promptly and initiate appropriate treatment, as this disease can lead to the deposition of uric acid crystals (so-called urate) in various joints and tissues if insufficient therapy is … Gout attack
Symptoms The symptoms of an acute attack of gout can vary from patient to patient both in intensity and duration. However, pain in the affected joints and in the surrounding tissue are among the typical symptoms of an acute attack of gout. In addition, all classic signs of inflammation can be detected in the joints. … Symptoms | Gout attack
