Products Cabazitaxel is released as a concentrate for the preparation of an infusion solution. It has been approved in many countries since 2011 (Jevtana). Structure and properties Cabazitaxel (C45H57NO14, Mr = 835.9 g/mol) is a taxane semisynthetically derived from a constituent of yew needles. It is structurally closely related to docetaxel, which is itself a … Cabazitaxel
Products Pertuzumab is commercially available as a concentrate for the preparation of an infusion solution (Perjeta). It was approved in many countries in 2012. Structure and properties Pertuzumab is a recombinant humanized IgG1 monoclonal antibody. It was developed as a successor to trastuzumab (Herceptin). Effects Pertuzumab (ATC L01XC13) has cytostatic and antiproliferative properties. The effects … Pertuzumab
The group of taxanes includes the active ingredients paclitaxel, docetaxel, and cabazitaxel. Their action is due to the disruption of cell division (mitosis), which medicine uses to treat various cancers. What are taxanes? Taxanes form a group of agents that belong to the cytostatic drugs and are also known as taxoids. They are used in … Taxanes: Effects, Uses & Risks
Products Docetaxel is commercially available as an infusion preparation (Taxotere, generics). It was approved in many countries in 1996 as a second taxane after paclitaxel (Taxol). Structure and properties Docetaxel (C43H53NO14, Mr = 807.9 g/mol) is present in the drug as docetaxel trihydrate, a white powder that is practically insoluble in water. The lipophilic drug … Docetaxel
Products Paclitaxel is commercially available as an infusion concentrate (Taxol, generic). It has been approved in many countries since 1993. The active ingredient itself is also known as taxol. Protein-bound nab-paclitaxel (Abraxane) was approved in many countries in 2014. Structure and properties Paclitaxel (C47H51NO14, Mr = 853.9 g/mol) is a complex tetracyclic diterpene. It exists … Paclitaxel
Symptoms Lung cancer may initially be asymptomatic. It is often discovered only when it is no longer curable. Possible typical symptoms include a chronic cough, coughing up blood, difficulty breathing, recurrent colds, chest pain, and weakness, fatigue, lack of appetite, and weight loss. If spread further, additional symptoms include hoarseness, noises when breathing, and difficulty … Lung Cancer Causes and Treatment
Hand-foot syndrome occurs more frequently during treatment with cytostatic drugs. Patients’ feet and hands become red, scaly, and painful or are affected by sensory disturbances. Hand-foot syndrome is treated symptomatically with analgesics and creams. What is hand-foot syndrome? Therapeutic drug treatments are usually associated with various side effects and health risks. In particular, phenomena such … Hand-foot Syndrome: Causes, Symptoms & Treatment
The cytostatic drug docetaxel belongs to the group of taxanes. It is used for the therapy of various cancers. What is docetaxel? Docetaxel is a cytostatic drug that belongs to the taxane group of drugs. The drug is produced by the French pharmaceutical company Sanofi. Docetaxel is a structural derivative of the cytostatic drug paclitaxel. … Docetaxel: Effects, Uses & Risks
