Cystic Fibrosis: Causes and Treatment

Symptoms In cystic fibrosis (CF, cystic fibrosis), different organ systems are affected, resulting in a heterogeneous clinical picture with symptoms of varying severity: Lower respiratory tract: Chronic cough with viscous mucus formation, obstruction, recurrent infectious diseases, e.g., with , inflammation, remodeling of the lungs (fibrosis), pneumothorax, respiratory insufficiency, shortness of breath, wheezing, oxygen deficiency. Upper … Cystic Fibrosis: Causes and Treatment

Therapeutic Enzymes

Products Enzymes are commercially available as drugs in the form of tablets, lozenges, capsules, as well as injection and infusion preparations, among others. Many products are subject to prescription, but there are also some agents which are released for the OTC market. Structure and properties Therapeutic enzymes are usually proteins, i.e. polymers of amino acids, … Therapeutic Enzymes

Dornase Alfa

Products Dornase alfa is commercially available as an inhalation solution (Pulmozyme). It has been approved in many countries since 1994. Structure and properties Dornase alfa is a genetically engineered variant of the enzyme human deoxyribonuclease I, which occurs naturally in humans. Effects Dornase alfa (ATC R05CB13) has mucolytic properties. It cleaves extracellular DNA in the … Dornase Alfa