How doxazosin works Doxazosin binds selectively to so-called alpha-1 receptors. These are binding sites in the nervous system, in the salivary glands, and also on smooth muscle. When the active ingredient occupies the receptors, they are blocked for the messenger substances that would otherwise bind here – such as adrenaline and noradrenaline. The active ingredient … Doxazosin: Effects, Uses, Side Effects
Symptoms Benign hyperplasia of the prostate is a typical and chronic age-related condition in men. Approximately 50% of men over 50 and 80% of men over 80 are affected. The incidence and symptoms increase with age. Age is therefore the most important risk factor. The clinical symptoms are also called “benign prostatic syndrome”, because the … Prostate Enlargement Causes and Treatment
Products Doxazosin is commercially available in the form of sustained-release film-coated tablets (Cardura CR, generic). It has been approved in many countries since 1999. Structure and properties Doxazosin (C23H25N5O5, Mr = 451.5 g/mol) is present in drugs as doxazosin mesilate, a quinazoline derivative and a white crystalline powder that is sparingly soluble in water. Effects … Doxazosin
Symptoms High blood pressure is often asymptomatic, meaning that no symptoms occur. Nonspecific symptoms such as headache, bleeding in the eye, nosebleeds, and dizziness are observed. In advanced disease, various organs such as the vessels, retina, heart, brain and kidney are affected. Hypertension is a known and important risk factor for atherosclerosis, dementia, cardiovascular diseases … Hypertension
Products Alpha blockers are available in many countries in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. The most commonly prescribed today is tamsulosin (Pradif T, generic). Alpha blocker is short for alpha1-adrenoreceptor antagonist. Structure and properties The first alpha blockers-alfuzosin, doxazosin, and terazosin-were developed as derivatives of quinazoline: Effects Alpha blockers (ATC … Alpha Blocker
