Products Most ACE inhibitors are commercially available in the form of tablets and film-coated tablets. The first agent from this group to be approved was captopril, in many countries in 1980. ACE inhibitors are often combined with the thiazide diuretic hydrochlorothiazide (HCT) fix. Structure and properties ACE inhibitors are peptidomimetics derived from peptides found in … ACE Inhibitors List, Effects, Side Effects
Products Pure malic acid is available in specialized stores. The name of the acid is derived from Latin (apple), because it was first isolated from apple juice in 1785. Structure and properties Malic acid (C4H6O5, Mr = 134.1 g/mol) is an organic dicarboxylic acid which belongs to the hydroxycarboxylic acids. It exists as a white … Malic Acid
Definition Thiols are organic compounds with the general structure R-SH. They are sulfur analogs of alcohols (R-OH). R can be aliphatic or aromatic. The simplest aliphatic representative is methanethiol, the simplest aromatic is thiophenol (analogue of phenol). Thiols are formally derived from hydrogen sulfide (H2S), in which a hydrogen atom has been replaced by a … Thiols
Products Valaciclovir is commercially available in the form of film-coated tablets (Valtrex, generic). It has been approved in many countries since 1995. Structure and properties Valaciclovir (C13H20N6O4, Mr = 324.3 g/mol) is the ester of the natural amino acid valine and the antiviral drug aciclovir. It is present in drugs as valaciclovir hydrochloride, a white … Valaciclovir
Products Boric acid is contained in eye drops as an excipient. In Germany, it belongs to the so-called “questionable prescription drugs” and should be used exclusively for healing waters and buffers in eye drops and for homeopathics (from D4). This is justified by a lack of efficacy and the risk of resorptive poisoning. This requirement … Boric Acid
Products Isopropyl myristate is found as an excipient in pharmaceuticals, primarily in semisolid dosage forms such as creams and gels, and in liquid preparations. Structure and properties Isopropyl myristate (C17H34O2, Mr = 270.5 g/mol) contains 1-methyl ethyl tetradecanoate along with varying amounts of other fatty acid isopropyl esters. It exists as a clear, colorless, oily … Isopropyl Myristate
Products Acetic anhydride is available in specialized stores. Structure and properties Acetic anhydride (C4H6O3, Mr = 102.09 g/mol) is the condensation product of two acetic acid molecules. It exists as a colorless liquid with a pungent odor of acetic acid. This is a result of hydrolysis with water: C4H6O3 (acetic anhydride) + H2O (water) 2 … Acetic Anhydride
Structure and properties Many active pharmaceutical ingredients are present in the drug as organic salts. This means that the active ingredient is ionized and its charge is neutralized by a counterion (English ). For example, naproxen is present in the over-the-counter pain reliever as a sodium salt. In this form, it is referred to as … Active Ingredient Salts
Products Acetic acid is available as an aqueous solution in various concentrations in pharmacies and drugstores. Structure and properties Acetic acid (C2H4O2, Mr = 60.1 g/mol) or CH3-COOH is the simplest carboxylic acid after formic acid. It consists of a methyl and carboxyl group. It exists as a pure substance as a clear, volatile, colorless … Acetic Acid
Products Candesartan is commercially available in tablet form (Atacand, Blopress, generics). It is also combined fixed with hydrochlorothiazide (Atacand plus, Blopress plus, generics). Candesartan has been approved in many countries since 1997. In 2020, a fixed combination with amlodipine was also released. Structure and Properties Candesartan (C24H20N6O3, Mr = 440.45 g/mol) is administered in the … Candesartan
Products Fumaric acid is used as an excipient in medicinal products. Active ingredients are also derived from it. Structure and properties Fumaric acid (C4H4O4, Mr = 116.1 g/mol) is a dicarboxylic acid. It exists as a white, crystalline and odorless powder or as crystals and is sparingly soluble in water. The pharmacopoeia defines it in … Fumaric Acid
Products Diroximelfumarate was approved in the United States in 2019 in the form of sustained-release capsules (Vumerity). It should not be confused with dimethyl fumarate (Tecfidera). Structure and properties Diroximelfumarate (C11H13NO6, Mr = of 255.2 g/mol) exists as a white powder that is sparingly soluble in water. The active metabolite monomethyl fumarate (MMF, see below) … Diroximelfumarate
