Alternative spelling Factor V Leiden Introduction/Definition Factor 5 Leiden, also known as APC resistance, is a disease that affects the body’s so-called coagulation system. The coagulation system ensures that when an injury occurs, the blood coagulates quickly, the bleeding is stopped and the wound can heal. In addition to the blood platelets (thrombocytes), there is … Factor 5 Leiden
Symptoms The Factor 5 Leiden itself does not cause any symptoms in the absence of bleeding. However, the disease interferes with the body’s coagulation system and causes a blood clotting disorder. This blood-clotting disorder is the reason why the probability of developing a blood clot increases dramatically. How much the probability of such an event … Symptoms | Factor 5 Leiden
Cause The cause of a factor 5 condition is genetic. A mutation in the gene responsible for the formation of the protein “Factor 5” makes this factor resistant to the activated protein C, which in turn leads to increased clotting. Factor 5 Leiden thus represents the best-known innate form of APC resistance. In most cases, … Cause | Factor 5 Leiden
Prognosis The individual prognosis in case of existing Factor 5 Leiden depends on whether the mutated gene is heterozygous, i.e. only once, or homozygous, i.e. twice. If the mutated gene has been passed on from mother and father to the child, i.e. if the affected person is homozygous, the probability of a blood clot occurring … Prognosis | Factor 5 Leiden
The Pill and Factor 5 Suffering The colloquially known “pill” includes the group of so-called anticonceptives. These are not only used for contraception, but can also be used for other gynecological diseases and for example the so-called iron deficiency anaemia. However, various undesirable side effects can occur. In particular, the estrogen contained in the pill … The Pill and Factor 5 Suffering | Factor 5 Leiden
Blood donation with factor 5 suffering – what should be considered? Since Factor 5 Leiden is not an infectious disease, but usually a congenital genetic change, a blood donation is in principle possible. However, since it is a blood coagulation disorder, many blood donation services exclude people with Factor 5 Leiden from donating blood. When … Blood donation with factor 5 suffering – what should be considered? | Factor 5 Leiden
