Flunitrazepam: Effects, Uses, Side Effects

How flunitrazepam works Flunitrazepam – like other members of the benzodiazepine class – acts as a so-called allosteric modulator at the GABA receptor. Allosteric modulators facilitate the binding of the natural messenger GABA to its binding site (receptor) without activating it themselves. Signal transmission between nerve cells in the brain occurs via narrow, gap-like contact … Flunitrazepam: Effects, Uses, Side Effects

Benzodiazepines Effects and Side Effects

Products Benzodiazepines are commercially available in the form of tablets, melting tablets, capsules, drops, and injectables, among others (selection). Chlordiazepoxide (Librium), the first benzodiazepine, was synthesized in the 1950s by Leo Sternbach at Hoffmann-La Roche and was launched in 1960. The second active ingredient, the well-known diazepam (Valium), was launched in 1962. Numerous other drugs … Benzodiazepines Effects and Side Effects

Gamma Hydroxybutyrate (GHB)

Products Gammahydroxybutyrate is commercially available as an oral solution (Xyrem). It has been approved in many countries since 2006. The drug belongs to narcotics and requires an aggravated prescription. GHB is also known to be manufactured and trafficked illegally. Structure and properties The free γ-hydroxybutyric acid (C4H8O3, Mr = 104.1 g/mol) is a colorless and … Gamma Hydroxybutyrate (GHB)

Narcotics Effects and Side Effects

Products The narcotics are a group of centrally acting drugs and substances, which are strongly regulated and controlled by the state respectively by the drug and health authorities. This is primarily to prevent abuse and to protect the population from the undesirable effects and addiction. Certain narcotics – for example, many potent hallucinogens – are … Narcotics Effects and Side Effects

Nitrazepam

Products Nitrazepam is commercially available in tablet form (Mogadon). It has been approved in many countries since 1965. Structure and properties Nitrazepam (C15H11N3O3, Mr = 281.3 g/mol) is a nitrated 1,4-benzodiazepine. It exists as a yellow crystalline powder that is practically insoluble in water. Nitrazepam is structurally closely related to flunitrazepam (Rohypnol). Effects Nitrazepam (ATC … Nitrazepam

Intoxicant

Products Legally, a distinction can be made between legal intoxicants (e.g., alcohol, nicotine) and prohibited substances (e.g., many hallucinogens, some amphetamines, opioids). Some substances, such as the opioids or the benzodiazepines, are used as drugs and are legally available with a doctor’s prescription. However, their use as intoxicants is not intended and is therefore referred … Intoxicant

Flunitrazepam

Products Flunitrazepam is commercially available in the form of film-coated tablets (Rohypnol). It has been approved in many countries since 1975. Structure and properties Flunitrazepam (C16H12FN3O3, Mr = 313.3 g/mol) is a lipophilic, fluorinated and nitrated 1,4-benzodiazepine. It exists as a white to yellowish crystalline powder that is practically insoluble in water. Effects Flunitrazepam (ATC … Flunitrazepam

Dyes in Medicines

Which dyes are used? Coloring agents that are also used as food additives (E-numbers) are usually used for medicines. Which colorants are permitted depends on the legislation of the relevant countries. For Switzerland, the specifications published in the Medicines Approval Ordinance (AMZV), in Pharmacopoea Helvetica and in the Additives Ordinance apply. The following list shows … Dyes in Medicines