Dispersible Tablets

Definition and properties Dispersible tablets are uncoated tablets or film-coated tablets that can be suspended or dissolved in water before ingestion. They are designated by the Pharmacopoeia as “tablets for the preparation of a suspension for ingestion” and “tablets for the preparation of a solution for ingestion.” When dissolved, a homogeneous suspension or solution is … Dispersible Tablets

Serotonin Syndrome: Causes and Treatment

Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment

Atomoxetine

Products Atomoxetine is commercially available in capsule form and as a drinkable solution (Strattera, generics). It was approved in many countries in 2009. Structure and properties Atomoxetine (C17H21NO, Mr = 255.4 g/mol) is present in drugs as atomoxetine hydrochloride. It is structurally closely related to the SSRI fluoxetine (Fluctine, Prozac, generics), which was also developed … Atomoxetine

Desloratadine

Products Desloratadine is commercially available as 5 mg film-coated tablets and as a solution (Aerius, generics). It has been approved in many countries since 2001. The syrup was replaced in 2011 by a solution that is sugar- and dye-free. The concentration remains identical (0.5 mg/ml). The fixed combination with pseudoephedrine is not yet available in … Desloratadine

Fluoxetine: Effects, Uses & Risks

Fluoxetine is a drug in the antidepressant drug class. The active ingredient belongs to the selective serotonin reuptake inhibitors (SSRIs). What is fluoxetine? Fluoxetine is used in Germany to treat depression. Fluoxetine is the second drug in the selective serotonin reuptake inhibitor (SSRI) generation, after zimelidine (now no longer approved). The first patent was granted … Fluoxetine: Effects, Uses & Risks