Products Follitropin alfa is commercially available as an injectable. It has been approved in many countries since 1995. Biosimilars are approved in some countries (Switzerland: Ovaleap, 2018). Structure and properties Follitropin alfa is a follicle-stimulating hormone (FSH) produced by biotechnological methods. It is a heterodimer and consists of two distinct glycoproteins, the α-subunit (92 amino … Follitropin Alfa
Products Follitropin beta is commercially available as a solution for injection (Puregon). It has been approved in many countries since 2001. Structure and properties Follitropin beta is a recombinant human follicle-stimulating hormone (FSH) produced by biotechnological methods. The amino acid sequence corresponds to human FSH. It differs from follitropin alfa in glycosylation. FSH is a … Follitropin Beta
Products Follitropin delta was approved in the EU in 2016 and in many countries in 2017 as [solution for injection>injections] (recovelle). Structure and properties Follitropin delta is a recombinant human follicle-stimulating hormone (FSH) with the same amino acid sequences as the natural hormone. Follitropin delta is produced in the human cell line PER.C6 and differs … Follitropin Delta
Products Urofollitropin is commercially available as an injectable (fostimone). It has been approved in many countries since 1996. Structure and properties Urofollitropin is a highly purified human follicle-stimulating hormone (FSH) derived from the urine of postmenopausal women. FSH is a heterodimer and consists of two distinct glycoproteins, the α-subunit (92 amino acids) and the β-subunit … Urofollitropin
Products Biosimilars are copycat preparations of biotechnology-derived drugs (biologics) that have strong similarities to the originator drugs but that are not exactly the same. The similarity relates to biological activity, structure, function, purity and safety, among other things. Biosimilars differ from generics of small molecule drugs in important ways. Biosimilars are usually marketed as injection … Biosimilars
