Follitropin Alfa

Products Follitropin alfa is commercially available as an injectable. It has been approved in many countries since 1995. Biosimilars are approved in some countries (Switzerland: Ovaleap, 2018). Structure and properties Follitropin alfa is a follicle-stimulating hormone (FSH) produced by biotechnological methods. It is a heterodimer and consists of two distinct glycoproteins, the α-subunit (92 amino … Follitropin Alfa

Follitropin Beta

Products Follitropin beta is commercially available as a solution for injection (Puregon). It has been approved in many countries since 2001. Structure and properties Follitropin beta is a recombinant human follicle-stimulating hormone (FSH) produced by biotechnological methods. The amino acid sequence corresponds to human FSH. It differs from follitropin alfa in glycosylation. FSH is a … Follitropin Beta

Follitropin Delta

Products Follitropin delta was approved in the EU in 2016 and in many countries in 2017 as [solution for injection>injections] (recovelle). Structure and properties Follitropin delta is a recombinant human follicle-stimulating hormone (FSH) with the same amino acid sequences as the natural hormone. Follitropin delta is produced in the human cell line PER.C6 and differs … Follitropin Delta

Urofollitropin

Products Urofollitropin is commercially available as an injectable (fostimone). It has been approved in many countries since 1996. Structure and properties Urofollitropin is a highly purified human follicle-stimulating hormone (FSH) derived from the urine of postmenopausal women. FSH is a heterodimer and consists of two distinct glycoproteins, the α-subunit (92 amino acids) and the β-subunit … Urofollitropin

Menotropin

Products Menotropin is commercially available as an injectable (Menopur, Merional HG, combination products). It has been used medicinally since the 1960s. Structure and properties Menotropin is a highly purified human menopausal gonadotropin (hMG, ) derived from human urine of postmenopausal women. Argentina and China are reported as the countries of origin. Menotropin is a mixture … Menotropin

Lutropin Alfa

Products Lutropin alfa is commercially available as an injectable (Luveris). It has been approved in many countries since 2002. Structure and properties Lutropin alfa is a is a recombinant human luteinizing hormone (LH). LH is a glycoprotein. Indications In combination with follicle-stimulating hormone (FSH) to stimulate follicular maturation in women with severe LH and FSH … Lutropin Alfa