furosemide

Furosemide: Drug Effects, Side Effects, Dosage and Uses

Products Furosemide is commercially available in the form of tablets, sustained-release capsules, and as a solution for injection (Lasix, generics). It has been approved in many countries since 1964 and is also used in fixed combination with the aldosterone antagonist spironolactone (Lasilactone, generic). Structure and properties Furosemide (C12H11ClN2O5S, Mr = 330.7 g/mol) exists as a … Furosemide: Drug Effects, Side Effects, Dosage and Uses

Aliskiren

Products Aliskiren is commercially available in the form of film-coated tablets (Rasilez, Rasilez HCT + hydrochlorothiazide). It was approved in many countries, in the EU and in the United States in 2007 (Other brand name: Tekturna). Note: Other combination preparations, e.g., with amlodpine (Rasilamlo), are no longer available. Structure and properties Aliskiren (C30H53N3O6, Mr = … Aliskiren

Diuretics

Synonyms in a broader sense water tablets, dehydration drugs, furosemide, thiazides Definition Diuretics are a group of drugs that lead to increased urinary excretion (diuresis). They are often referred to as “water tablets” kidneys, because they increase the excretion of fluids over the They are used in the treatment of high blood pressure, to flush … Diuretics

Side effects | Diuretics

Side effects Every drug has side effects – this is also the case with diuretics.The different groups of diuretics also have a different side effect profile, but some side effects are found in all drugs. In general, each drug carries the risk of developing hypersensitivity or allergy. This can lead to skin rashes, discomfort and … Side effects | Diuretics

Spironolactone

Products Spironolactone is commercially available in film-coated tablet form as a monopreparation (Aldactone) and in fixed combination with furosemide (Furospir). It was developed in the 1950s at G.D. Searle in Chicago and approved in 1959, and in many countries in 1961. Structure and properties Spironolactone (C24H32O4S, Mr = 416.6 g/mol) exists as a white to … Spironolactone

Loop Diuretics

Products Loop diuretics are commercially available as tablets, sustained-release capsules, and injection and infusion preparations. Torasemide and furosemide are the most commonly used in many countries today. Structure and properties Available loop diuretics are usually sulfonamide or sulfonylurea derivatives. Representatives without a sulfonamide structure also exist, for example, the phenoxyacetic acid derivative etacrynic acid. Effects … Loop Diuretics

Hyperkalemia (High Potassium)

Background Potassium ions play an important role in many biological processes, particularly in the generation of membrane and action potentials and electrical conduction in nerve cells and the heart. Potassium is 98% localized intracellularly. The primary active transporter Na+/K+-ATPase provides transport into cells. Two hormones maintain the deep extracellular potassium concentration. The first is insulin, … Hyperkalemia (High Potassium)

Furosemide: Effects, Uses & Risks

Furosemide is the name given to a loop diuretic. The drug has a diuretic effect and is used for edema or high blood pressure. What is furosemide? The active ingredient furosemide belongs to the drug group of loop diuretics. These have the property of excreting larger amounts of tissue fluid from the body, which is … Furosemide: Effects, Uses & Risks

Hypokalemia (Low Potassium)

Background Potassium ions play an important role in many biological processes, particularly in the generation of membrane and action potentials and electrical conduction in nerve cells and the heart. Potassium is 98% localized intracellularly. The primary active transporter Na+/K+-ATPase provides transport into cells. Two hormones maintain the deep extracellular potassium concentration. The first is insulin, … Hypokalemia (Low Potassium)

Norepinephrine

Products Norepinephrine is commercially available as a solution for injection in many countries. It is also known as norepinephrine. Structure and properties Norepinephrine (C8H11NO3, Mr = 169.2 g/mol) is a demethylated epinephrine. It is present in drugs as noradrenaline tartrate, a white crystalline powder that is readily soluble in water. Effects Norepinephrine (ATC C01CA03) has … Norepinephrine