Products Filgrastim is commercially available as a solution for injection in vials and prefilled syringes (Neupogen, biosimilars). It has been approved in many countries since 1991. Structure and properties Filgrastim is a protein of 175 amino acids produced by biotechnology. The sequence corresponds to human granulocyte colony-stimulating factor (G-CSF, Mr = 18,800 Da) with the … Filgrastim
Products Pegfilgrastim is commercially available as a solution for injection in the form of prefilled syringes (Neulasta). It has been approved in many countries since 2003. Biosimilars have been approved. Structure and properties Pegfilgrastim is a conjugate of filgrastim with a single 20-kDa polyethylene glycol (PEG) molecule. Filgrastim is a protein of 175 amino acids … Pegfilgrastim
Products Lenograstim is commercially available as an injection/infusion preparation (Granocyte). It has been approved in many countries since 1993. Structure and properties Lenograstim is a protein of 174 amino acids produced by biotechnology. The sequence corresponds to human granulocyte colony-stimulating factor (G-CSF). Unlike filgrastim, lenograstim is identical to G-CSF and is glycosylated. Effects Lenograstim (ATC … Lenograstim
G-CSF is a peptide hormone that stimulates the formation of granulocytes. Thus, it possesses great importance in the function of the immune system. The hormone is also given as a drug to patients with a severely weakened immune system to stimulate the formation of neutrophilic white blood cells. What is G-CSF? G-CSF is the abbreviation … G-CSF: Function & Diseases
