Cortisone itself is basically not an effective drug, because the hormonal drug known as cortisone usually does not contain the inactive cortisone, but its active form cortisol (hydrocortisone). Cortisone is converted by enzymes into the actual active substance cortisol. Both cortisone and its active form belong to the group of steroid hormones. Steroid hormones are … Effect of cortisone
Mode of action Cortisone penetrates the cell wall of a body cell and binds to a suitable cortisone receptor inside the cell. These glucocorticoid receptors are found almost everywhere in the body, but they are found in greater numbers in the muscles, fatty tissue, skin, liver and lymphatic tissue. This active substance-receptor complex migrates into … Mode of action | Effect of cortisone
Undesirable effects The adverse effects of cortisone are directly related to the desired effects. Because cortisone interferes with the sugar, protein and bone metabolism as well as with the body’s water balance, the intake of high doses of cortisone over a longer period of time can, for example, lead to permanently elevated blood sugar levels … Undesirable effects | Effect of cortisone
Gluconeogenesis ensures the re-synthesis of glucose from pyruvate, lactate and glycerol in the body. In this way, it ensures the glucose supply of the organism during periods of starvation. Disturbances in gluconeogenesis can lead to dangerous hypoglycemia. What is gluconeogenesis? Gluconeogenesis reactions occur mainly in the liver and muscles. During gluconeogenesis, glucose is produced again … Gluconeogenesis: Function, Role & Diseases
