Cortisone therapy Cortisone is used in Crohn’s disease primarily for the treatment of acute relapses. It can be administered systemically as a tablet or in some cases locally as an enema or klysma. In mild to moderate attacks, cortisone preparations almost always lead to an improvement in symptoms. Even the most severe relapses can be … Cortisone therapy | Medicines for Crohn’s disease
Biologics Biologics (also known as biologicals or biopharmaceuticals) are drugs that are very similar or similar to the body’s own proteins. In the case of Crohn’s disease, for example, antibodies are used that attack very specific cells or even just molecules of the body and thus fight inflammation. Adalimumab and Infliximab, both of which are … Biologics | Medicines for Crohn’s disease
Medicines for joint pain in Crohn’s disease Joint pain is a common side effect of Crohn’s disease. Sometimes the joints are also inflamed (arthritis), but more often there is joint pain without signs of inflammation. In an acute episode, large joints are usually affected, while in remission it is mainly the small joints that cause … Medicines for joint pain in Crohn’s disease | Medicines for Crohn’s disease
Products Biosimilars are copycat preparations of biotechnology-derived drugs (biologics) that have strong similarities to the originator drugs but that are not exactly the same. The similarity relates to biological activity, structure, function, purity and safety, among other things. Biosimilars differ from generics of small molecule drugs in important ways. Biosimilars are usually marketed as injection … Biosimilars
Symptoms Crohn’s disease manifests as inflammation that occurs primarily in the lower portion of the small intestine and in the colon. The typical course is chronically recurrent, meaning periods of quiescence are interrupted by episodes of disease. Common symptoms include: Abdominal pain (more likely on the right side) Nausea, vomiting Diarrhea, constipation Flatulence Fever Weight … Crohn’s Disease Causes and Treatment
Introduction The immune system is essential for the survival of every human being. In the course of evolution, the human immune system has evolved into the so-called adaptive immune system. This gives us the possibility to react more differentiated and effective to bacteria and viruses. The immune system protects us. It helps us to better … Biologics
Active substance/effect Most biologics are proteins. There are different generations of biologics and therefore also of TNF-α inhibitors. The generations differ from the production. The ending of the name tells how much mouse protein is still present in the active ingredients. With the ending -omab there is 100%, with the ending -ximab there is still … Active substance/effect | Biologics
Dosage Since the bilogikas are usually proteins, they must be given parenterally (via an infusion). Oral administration is not possible, as the body would then digest them and the active ingredients would not be able to exert their effect. The dosage depends on the active ingredient and the disease in question. Usually the dose is … Dosage | Biologics
When should biologicals not be taken? If there is a previous history of tuberculosis, TNF-α inhibitors must not be used. This is independent of how long ago the tuberculosis occurred. The reason for this is that inactivated tuberculosis bacteria are still present in the body once someone has contracted tuberculosis. These tuberculosis bacteria are inactive … When should biologicals not be taken? | Biologics
