Products Azathioprine is commercially available as film-coated tablets and as a lyophilizate (Imurek, generic). It has been approved in many countries since 1965. Structure and properties Azathioprine (C9H7N7O2S, Mr = 277.3 g/mol) is a nitromidazole derivative of mercaptopurine. It exists as a pale yellow powder that is practically insoluble in water. Effects Azathioprine (ATC L04AX01) … Azathioprine (Imuran)
Products Infliximab is commercially available as a powder for a concentrate for the preparation of an infusion solution (Remicade, biosimilars: Remsima, Inflectra). It has been approved in many countries since 1999. Biosimilars were released in 2015. Structure and properties Infliximab is a chimeric human murine IgG1κ monoclonal antibody with a molecular mass of 149.1 kDa … Infliximab: Drug Effects, Side Effects, Dosage and Uses
Symptoms Rheumatoid arthritis is a chronic, inflammatory and systemic joint disease. It manifests as pain, symmetrically tense, achy, warm, and swollen joints, swelling, and morning stiffness that lasts for more than an hour. Initially, the hands, wrists, and feet are most affected, but later numerous other joints are also affected. Over time, deformities and rheumatoid … Rheumatoid Arthritis Causes and Treatment
Products TNF-α inhibitors are commercially available as injectable and infusion preparations. Infliximab (Remicade) was the first agent from this group to be approved in 1998, and in many countries in 1999. Biosimilars of some representatives are now available. Others will follow in the next few years. This article refers to biologics. Small molecules can also … TNF-Α Inhibitors
Symptoms Typical symptoms of agranulocytosis include fever, chills, feeling ill, tonsillitis, sore throat, difficulty swallowing, and lesions and bleeding of the oral, nasal, pharyngeal, genital, or anal mucosa. The disease can lead to dangerous infections and blood poisoning and, if left untreated, can relatively often be fatal. Agranulocytosis usually occurs rarely to very rarely as … Agranulocytosis Symptoms and Treatment
Symptoms Psoriasis is a chronic inflammatory, benign, and noninfectious skin disease. It manifests as symmetrical (bilateral), sharply demarcated, bright red, dry, raised plaques covered by silvery scales. Typically affected areas are the elbows, knees, and scalp. Itching, a burning sensation and pain are other symptoms, and scratching further aggravates the condition. Psoriasis can also affect … Psoriasis Causes and Treatment
Products The first therapeutic monoclonal antibody was approved in 1986. Muromonab-CD3 (Orthoclone OKT3) binds to the CD3 receptor on T cells and has been used in transplantation medicine. Numerous drugs containing antibodies are now available. A selection of active substances can be found at the end of this article. These are expensive drugs. For example, … Monoclonal Antibodies
What medications are used in the event of a relapse? Which drugs are used in the relapse depends on the severity of the individual relapse. A mild episode without fever and only a few bloody diarrhoea cases can be treated well in most cases with Salofalk alone. Salofalk® (mesalazine) can be given in the form … What medications are used in the event of a relapse? | Medicines for colitis ulcerosa
Are there also over-the-counter medications available? The drugs of the normal therapy regime are all prescription. Since many of the drugs, especially cortisone and immunosuppressants, can cause serious side effects, they may only be prescribed by doctors. This enables the treating physician to regularly monitor the patient’s symptoms, as Ulcerative colitis in relapse is a … Are there also over-the-counter medications available? | Medicines for colitis ulcerosa
Introduction Ulcerative colitis is initially treated with drugs both in the non-inflammatory phase and in the acute inflammatory phase. The choice of medication depends on the cause of the therapy and the severity of the disease. The fact that there are different groups of drugs with varying degrees of anti-inflammatory effect means that the therapy … Medicines for colitis ulcerosa
Products Immunosuppressants are commercially available in numerous dosage forms, for example, as creams, ointments, tablets, capsules, solutions, eye drops, and injectables. Structure and properties Within immunosuppressants, several groups can be identified. These include steroids such as the glucocorticoids, substances of microbiological origin such as ciclosporin and mycophenolate mofetil, derivatives of nucleic acids and their components … Immunosuppressants
Introduction Crohn’s disease is a so-called chronic inflammatory bowel disease, or CED for short. It progresses in relapses and is not curable. For this reason, patients are usually forced to take medication throughout their lives to prevent new relapses (remission maintenance). Whereas a few decades ago cortisone was the only known drug for the treatment … Medicines for Crohn’s disease
