Edoxaban

Products Edoxaban was approved in many countries and in the United States in 2015 in film-coated tablet form (Lixiana, some countries: Savaysa). In Japan, edoxaban was approved as early as 2011. Structure and properties Edoxaban (C24H30ClN7O4S, Mr = 548.1 g/mol) is present in the drug as edoxabantosilate monohydrate, a white to pale yellow powder that … Edoxaban

Finasteride

Products Finasteride is commercially available as film-coated tablets (prostate: Proscar, generic, 5 mg; hair loss: Propecia, generic, 1 mg). It has been approved in many countries since 1993. Propecia was launched five years later, in 1998. Structure and properties Finasteride (C23H36N2O2, Mr = 372.5 g/mol) is a 4-azasteroid and structurally related to testosterone. It exists … Finasteride

Apixaban

Products Apixaban has been approved in many countries since 2011 in the form of film-coated tablets (Eliquis). Structure and properties Apixaban (C25H25N5O4, Mr = 460.0 g/mol) was developed starting from razaxaban. It is an oxopiperidine and pyrazole derivative. Effects Apixaban (ATC B01AF02) has antithrombotic properties. It is an oral, direct, potent, selective, and reversible inhibitor … Apixaban

Irbesartan

Products Irbesartan is commercially available in the form of film-coated tablets as a monopreparation (Aprovel, generic) and as a fixed combination with hydrochlorothiazide (Co-Aprovel). It has been approved in many countries since 1997. Generics entered the market in many countries in August 2012. Generic versions of the combination preprinted with hydrochlorothiazide went on sale in … Irbesartan

Somatostatin

Synonym: somatotropin-inhibitory hormone (SIH) Somatostatin is a third hormone, besides insulin and glucagon, which is produced in the pancreas. It is a messenger substance of the human body, which mainly inhibits the digestive process. It is also considered the antagonist of numerous other hormones in the body. Education Somatostatin is produced in the D-cells of … Somatostatin

Dutasteride

Products Dutasteride is commercially available in capsule form (Avodart). It is also available in combination with the alpha blocker tamsulosin (Duodart); see dutasteride tamsulosin. The active ingredient has been approved in many countries since 2003. Generics were registered in 2017. Generic versions of Duodart were approved in 2018. Structure and properties Dutasteride (C27H30F6N2O2, Mr = … Dutasteride

Dutasteride, Tamsulosin

Products The 5alpha-reductase inhibitor dutasteride and the alpha-blocker tamsulosin are commercially available as a fixed combination in the form of capsules (Duodart, generics). The drug has been approved in many countries since 2010. Structure and properties Dutasteride (C27H30F6N2O2, Mr = 528.5 g/mol) is a 4-azasteroid and structurally closely related to finasteride. It exists as a … Dutasteride, Tamsulosin

Fluconazole

Products Fluconazole is commercially available in capsule form, as a powder for suspension, and as an infusion solution (Diflucan, generic). It has been approved in many countries since 1989. Structure and properties Fluconazole (C13H12F2N6O, Mr = 306.3 g/mol) is a fluorinated triazole derivative. It exists as a white, crystalline and hygroscopic powder that is sparingly … Fluconazole