Products Ziconotide is commercially available as an infusion solution (Prialt). It has been approved in many countries since 2006. Structure and properties Ziconotide (C102H172N36O32S7, Mr = 2639 g/mol) is a peptide of 25 amino acids with three disulfide bridges. It is a synthetic analog of the ω-conopeptide MVIIA, which occurs in the venom of the … Ziconotide
Products Nusinersen was approved in the United States in 2016 and in many countries and the EU in 2017 as a solution for intrathecal injection by lumbar puncture and as the first drug for SMA treatment (Spinraza). Structure and properties Nusinersen is a modified antisense oligonucleotide. Effects Nusinersen (ATC M09AX07) increases the formation of the … Nusinersen
Products Cytarabine is commercially available as an injectable. It has been approved in many countries since 1971. Structure and properties Cytarabine (C9H13N3O5, Mr = 243.2 g/mol) exists as a white crystalline powder that is readily soluble in water. It is a synthetic pyrimidine. Effects Cytarabine (ATC L01BC01) has cytotoxic properties. It is a pyrimidine antagonist. … Cytarabine
Products Baclofen is commercially available as in tablet form and as a solution for injection (Lioresal, generics). It has been approved in many countries since 1970. Structure and properties Baclofen (C 10 H 12 ClNO 2 , M r = 213.7 g/mol) exists as a white and odorless powder that is sparingly soluble in water. … Baclofen
