Synonyms in a broader sense Proton pump inhibitors, PPI, active ingredients with the suffix -prazole (e.g. Pantoprazole), Antra® pump inhibitors Introduction Normally there is a balance in the stomach between the production of the aggressive gastric acid and the protective mechanisms of mucus and hydrogen carbonate formation. For the production of gastric acid, the vascular … Omeprazole
Pharmacokinetics of Omeprazole Omeprazole has its site of action at the proton pumps, which are located at the document cell membrane and point towards the stomach lumen. In order to reach the document cell, however, the substance omeprazole must not already be activated in the stomach. Therefore, the drug is administered as an acid-proof capsule. … Pharmacokinetics of Omeprazole | Omeprazole
Side effects of Omeprazole Omeprozole is generally well tolerated. Even when high doses are administered and the duration of therapy is long, side effects rarely occur. 1-2% of patients complain of gastrointestinal complaints. As a rule, this is due to an altered bacterial colonization of the gastrointestinal tract, because the stomach acid normally ensures that … Side effects of Omeprazole | Omeprazole
Interactions of omeprazole with other drugs Omeprazole may slow down the breakdown of other medicines such as diazepam (psychotropic drug), phenytoin (medicine for heart rhythm disturbances or seizures) or warfarin (anticoagulant). Contraindications of Omeprazole Omeprazole must not be given in cases of severe liver dysfunction. Another contraindication is the simultaneous administration of clopidogrel. Clopidogrel is … Interactions of omeprazole with other drugs | Omeprazole
