Loperamide: Effects, Uses, Side Effects

How loperamide works Loperamide acts on the so-called opioid receptors in the intestine, which are docking sites for certain hormones (endorphins) that slow down intestinal transit. The dampened movements of the colon result in increased absorption of water from the digestive pulp, thickening it – stopping diarrhea. Many other opioids, such as fentanyl, as well … Loperamide: Effects, Uses, Side Effects

Indian Psyllium

Products Indian psyllium seeds and Indian psyllium husks are available in pharmacies and drugstores as open goods. There are also corresponding finished medicines on the market, such as Agiolax mite, Laxiplant, and Metamucil. These are usually powders or granules. See also under psyllium. Stem plant The parent plant is from the plantain family (Plantaginaceae). The … Indian Psyllium

Dispensing Categories of Medicinal Products

Definition The dispensing of licensed medicines is strictly regulated by law in many countries. Drugs may be available by prescription (prescription-only), nonprescription, and over-the-counter. Typical dispensing points are pharmacies, drugstores and doctors’ offices, provided that self-dispensing is permitted by the canton. Category E drugs may also be sold in the retail trade, for example in … Dispensing Categories of Medicinal Products

Home Pharmacy

Tips The composition is individual and depends on the people in the household. Consider special patient groups and their needs: Babies, children, pregnant women, elderly (contraindications, interactions). Check expiration dates annually, return expired remedies to the pharmacy. Keep out of reach of children. Store at room temperature, closed and dry (not in the bathroom where … Home Pharmacy

Shigellosis

Symptoms The possible symptoms of shigellosis include: Watery or bloody, mucopurulent diarrhea. Inflammatory colitis (colitis). Dehydration Fever Abdominal pain, cramps Painful urge to defecate Nausea, vomiting The disease often occurs in children and usually lasts about a week. The severity varies and depends on the pathogen. Rarely, severe complications such as colonic perforation and hemolytic … Shigellosis

Eluxadoline

Products Eluxadoline was approved in the form of film-coated tablets in the US in 2015, in the EU in 2016, and in many countries in 2018 (US: Viberzi, EU, CH: Truberzi). Structure and properties Eluxadoline (C32H35N5O5, Mr = 569.7 g/mol) Effects Eluxadoline (ATC A07DA06) has antidiarrheal and analgesic properties. It is an agonist at μ-opioid … Eluxadoline

Norovirus

Symptoms Infection with norovirus manifests as gastroenteritis with diarrhea without blood in the stool and/or with violent, even explosive vomiting. Vomiting is more common in children. Furthermore, accompanying symptoms such as nausea, bloating, abdominal pain, abdominal cramps, muscle pain, headache, and mild fever may occur. An asymptomatic course is also possible. The duration of the … Norovirus

Diphenoxylate

Products Diphenoxylate is not commercially available in many countries. Combination products with atropine sulfate are commercially available in the United States. Structure and properties Diphenoxylate (C30H32N2O2, Mr = 452.6 g/mol) is present in drugs as diphenoxylate hydrochloride, a white crystalline powder that is very sparingly soluble in water. It is a derivative of pethidine and … Diphenoxylate

Traveler’s Diarrhea

Symptoms Traveler’s diarrhea is usually defined as a diarrheal illness that occurs in travelers from industrialized countries during or after a visit to a high-risk area, such as Latin America, Africa, the Middle East, or Asia. It is the most common travel illness, affecting 20% to 60% of travelers. Depending on the pathogen and severity, … Traveler’s Diarrhea

Irritable Bowel Syndrome Causes and Treatment

Symptoms Irritable bowel syndrome is a functional bowel disorder that manifests itself in the following persistent or recurrent symptoms: Lower abdominal pain or cramping Diarrhea and/or constipation Flatulence Change in bowel habits, impaired defecation. Incontinence, urge to defecate, feeling of incomplete emptying. The symptoms improve with defecation. Some patients suffer mainly from diarrhea, others from … Irritable Bowel Syndrome Causes and Treatment

Haloperidol

Products Haloperidol is commercially available as tablets, drops (Haldol), and as a solution for injection (Haldol, Haldol decanoas). It has been approved in many countries since 1960. Structure and properties Haloperidol (C21H23ClFNO2, Mr = 375.9 g/mol) is a derivative of pethidine, which is itself derived from atropine. It has structural similarity to loperamide. Haloperidol exists … Haloperidol

Difenoxin

Products Difenoxin is not commercially available in many countries. Structure and properties Difenoxin (C28H28N2O2, Mr = 424.5 g/mol) is the active metabolite of diphenoxylate and structurally related to loperamide (Imodium). Effects Difenoxin (ATC A07DA04) is peristaltic inhibitory and antidiarrheal. Indication Diarrhea